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Restrict the search for
phenyl aminosalicylate
to a specific field?
Status:
Investigational
Source:
INN:balamapimod [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Balamapimod, also known as MKI 833, a mitogen-activated protein kinase (Ras/Raf/MEK) inhibitor with potential anti-tumor activity. This compound can be used for the treatment of diseases that are results of deregulation of Ras/Raf/MEK kinases.
Status:
Investigational
Class (Stereo):
CHEMICAL (RACEMIC)
Enpiroline (WR 180,409) is an antimalarial compound. It demonstrates activity against Plasmodium falciparum both in vitro and in non-immune infected subjects. Additionally, it exerts antischistosomal activity.
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Telupidine (GR53992B), a dihydropyridine derivative is a calcium channel blocker. This is an antihypertensive and cardiovascular agent. Information about the current use of this compound is not available.
Status:
Investigational
Source:
NCT01483833: Phase 2 Interventional Completed Hemorrhoids
(2001)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Status:
Investigational
Source:
NCT00248183: Phase 3 Interventional Completed Anxiety Disorders
(2005)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Naluzotan (PRX-00023), a small molecule, non-azapirone, dual serotonin (5-HT)1A receptor agonist and sigma-1 receptor antagonist, is under development with Proximagen for the treatment of epilepsy. In previous clinical trials, the compound was shown to be safe and well-tolerated in over 400 patients. Epilepsy patients with localisation-related epilepsy have reduced 5-HT1a receptor binding as indicated by positron emission tomography (PET scan). It is thought that by increasing neurotransmitter activity at 5-HT1a receptor sites, seizure incidence and severity may be decreased.
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sulazepam is a desmethylbenzodiazepine. It is the thioamide derivative of diazepam. It has sedative, muscle relaxant, hypnotic, anticonvulsant and anxiolytic properties like those of other benzodiazepines. Sulazepam in vivo in experimental animals undergoes enzymic desulfonation, demethylation, and [3C] hydroxylation, with the formation of basic metabolites: diazepam, desmethyldiazepam, and oxazepam.
Status:
Investigational
Source:
NCT02364206: Phase 1/Phase 2 Interventional Completed Adult Glioblastoma
(2015)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Ralimetinib (LY2228820), a trisubstituted imidazole derivative, is a potent and selective, ATP-competitive inhibitor of the α- and β-isoforms of p38 mitogen-activated protein kinase. LY2228820 produced significant tumor growth delay in multiple in vivo cancer models (melanoma, non-small cell lung cancer, ovarian, glioma, myeloma, breast). Eli Lilly is developing ralimetinib for the treatment of cancer.
Status:
Investigational
Class (Stereo):
CHEMICAL (MIXED)
Clemeprol is an antidepressant drug of the 3,3-diraylpropyl-amine type. It exhibits antireserpine activity in animal tests, inhibits the neuronal uptake of noradrenaline. The drug was used in the clinic for the treatment of depression in the 1980s, but no development was reported since.
Status:
Investigational
Source:
INN:octabenzone [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Octabenzone is a UV absorber/screener. It is used to protect polymers (e.g., polyethylene, polypropylene, polyvinylchloride) against damage by UV light.
Status:
Investigational
Source:
INN:betacetylmethadol [INN]
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Betacetylmethadol is a synthetic narcotic analgesic under international control according to the UN Single Convention 1961.
