TELUDIPINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C28H38N2O6
Molecular Weight	498.6111
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)C1=C(C)NC(CN(C)C)=C(C1C2=C(\C=C\C(=O)OC(C)(C)C)C=CC=C2)C(=O)OCC

InChI

InChIKey=DKLVJXTUCNPMDC-FOCLMDBBSA-N

InChI=1S/C28H38N2O6/c1-9-34-26(32)23-18(3)29-21(17-30(7)8)25(27(33)35-10-2)24(23)20-14-12-11-13-19(20)15-16-22(31)36-28(4,5)6/h11-16,24,29H,9-10,17H2,1-8H3/b16-15+

HIDE SMILES / InChI

Molecular Formula	C28H38N2O6
Molecular Weight	498.6111
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Description
Sources: https://www.genome.jp/dbget-bin/www_bget?dr:D06060 | https://www.ncbi.nlm.nih.gov/pubmed/7806087

Telupidine (GR53992B), a dihydropyridine derivative is a calcium channel blocker. This is an antihypertensive and cardiovascular agent. Information about the current use of this compound is not available.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Calcium channel 4 Target ID: Calcium channel Sources: https://www.ncbi.nlm.nih.gov/pubmed/7806087	Blocker 555

PubMed

Title	Date	PubMed
Effects of R-enantiomer (GR66234A) and L-enantiomer (GR66235A) of telupidine, a new dihydropyridine derivative, on cell lines displaying the multidrug resistant phenotype.	1994-07-01	7806087

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:42:21 GMT 2025` Edited by `admin` on `Wed Apr 02 09:42:21 GMT 2025`
Record UNII	Z9OJ72BM3O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TELUDIPINE

Official Name

English

3,5-PYRIDINEDICARBOXYLIC ACID, 2-((DIMETHYLAMINO)METHYL)-4-(2-(3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL)PHENYL)-1,4-DIHYDRO-6-METHYL-, DIETHYL ESTER

Preferred Name

English

4-(O-((E)-2-CARBOXYVINYL)PHENYL)-2-((DIMETHYLAMINO)METHYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID, 4-TERT-BUTYL DIETHYL ESTER

Common Name

English

teludipine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C333