TELUDIPINE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C28H38N2O6.ClH
Molecular Weight	535.072
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCOC(=O)C1=C(C)NC(CN(C)C)=C(C1C2=C(\C=C\C(=O)OC(C)(C)C)C=CC=C2)C(=O)OCC

InChI

InChIKey=VMZCXIGDNRMWGI-GEEYTBSJSA-N

InChI=1S/C28H38N2O6.ClH/c1-9-34-26(32)23-18(3)29-21(17-30(7)8)25(27(33)35-10-2)24(23)20-14-12-11-13-19(20)15-16-22(31)36-28(4,5)6;/h11-16,24,29H,9-10,17H2,1-8H3;1H/b16-15+;

HIDE SMILES / InChI

Molecular Formula	C28H38N2O6
Molecular Weight	498.6111
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	1
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.genome.jp/dbget-bin/www_bget?dr:D06060 | https://www.ncbi.nlm.nih.gov/pubmed/7806087

Telupidine (GR53992B), a dihydropyridine derivative is a calcium channel blocker. This is an antihypertensive and cardiovascular agent. Information about the current use of this compound is not available.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Calcium channel 4 Target ID: Calcium channel Sources: https://www.ncbi.nlm.nih.gov/pubmed/7806087	Blocker 555

PubMed

Title	Date	PubMed
Effects of R-enantiomer (GR66234A) and L-enantiomer (GR66235A) of telupidine, a new dihydropyridine derivative, on cell lines displaying the multidrug resistant phenotype.	1994-07-01	7806087

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:30:53 GMT 2025` Edited by `admin` on `Mon Mar 31 18:30:53 GMT 2025`
Record UNII	7P6B96QLKN
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GR 53992B

Preferred Name

English

TELUDIPINE HYDROCHLORIDE

Official Name

English

3,5-PYRIDINEDICARBOXYLIC ACID, 2-((DIMETHYLAMINO)METHYL)-4-(2-(3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL)PHENYL)-1,4-DIHYDRO-6-METHYL-, DIETHYL ESTER, MONOHYDROCHLORIDE, (E)-

Systematic Name

English

TELUDIPINE HCL

Common Name

English

TALUDIPINE HYDROCHLORIDE

Common Name

English

GX 1296B

Code

English

3,5-PYRIDINEDICARBOXYLIC ACID, 2-((DIMETHYLAMINO)METHYL)-4-(2-((1E)-3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL)PHENYL)-1,4-DIHYDRO-6-METHYL-, DIETHYL ESTER, MONOHYDROCHLORIDE

Systematic Name

English

GX-1296B

Code

English

3,5-PYRIDINEDICARBOXYLIC ACID, 2-((DIMETHYLAMINO)METHYL)-4-(2-((1E)-3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPEN-1-YL)PHENYL)-1,4-DIHYDRO-6-METHYL-, 3,5-DIETHYL ESTER, HYDROCHLORIDE (1:1)

Systematic Name

English

GR-53992B

Code

English

TELUDIPINE HYDROCHLORIDE [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C333