TELUDIPINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C28H38N2O6
Molecular Weight	498.6111
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC(=O)C1=C(C)NC(CN(C)C)=C(C1C2=CC=CC=C2\C=C\C(=O)OC(C)(C)C)C(=O)OCC

InChI

InChIKey=DKLVJXTUCNPMDC-FOCLMDBBSA-N

InChI=1S/C28H38N2O6/c1-9-34-26(32)23-18(3)29-21(17-30(7)8)25(27(33)35-10-2)24(23)20-14-12-11-13-19(20)15-16-22(31)36-28(4,5)6/h11-16,24,29H,9-10,17H2,1-8H3/b16-15+

HIDE SMILES / InChI

Description
Sources: https://www.genome.jp/dbget-bin/www_bget?dr:D06060 | https://www.ncbi.nlm.nih.gov/pubmed/7806087

Telupidine (GR53992B), a dihydropyridine derivative is a calcium channel blocker. This is an antihypertensive and cardiovascular agent. Information about the current use of this compound is not available.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Calcium channel 4 Target ID: Calcium channel Sources: https://www.ncbi.nlm.nih.gov/pubmed/7806087	Blocker 537

PubMed

Title	Date	PubMed

Patents

Name

Type

Language

TELUDIPINE

Official Name

English

4-(O-((E)-2-CARBOXYVINYL)PHENYL)-2-((DIMETHYLAMINO)METHYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID, 4-TERT-BUTYL DIETHYL ESTER

Common Name

English

teludipine [INN]

Common Name

English

3,5-PYRIDINEDICARBOXYLIC ACID, 2-((DIMETHYLAMINO)METHYL)-4-(2-(3-(1,1-DIMETHYLETHOXY)-3-OXO-1-PROPENYL)PHENYL)-1,4-DIHYDRO-6-METHYL-, DIETHYL ESTER

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C333