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Restrict the search for
chloroquine
to a specific field?
Status:
Possibly Marketed Outside US
First approved in 2006
Source:
Embutramide by PROCOS S.p.A.
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Embutramide is a veterinary, CNS active medicine used for euthanasia in dogs. The drug is marketed under the name Tributame in the USA and under the name Tanax in Europe. Human consumption of the drug is usually associated with suicide attempts.
Status:
Possibly Marketed Outside US
Source:
Octaplasma by Octapharma Pharmazeutika Produktionsges M B H [Canada]
Source URL:
First approved in 2013
Source:
BLA125416
Source URL:
Class:
MIXTURE
Status:
Investigational
Source:
NCT03534063: Not Applicable Interventional Completed Pain, Postoperative
(2018)
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT04387760: Phase 2 Interventional Completed SARS-CoV 2
(2020)
Source URL:
Class:
STRUCTURALLY DIVERSE
Status:
Investigational
Source:
NCT03867331: Phase 1 Interventional Completed Malaria,Falciparum
(2019)
Source URL:
Class:
STRUCTURALLY DIVERSE
Status:
US Approved Rx
(2004)
Source:
ANDA076523
(2004)
Source URL:
First approved in 1989
Source:
LARIAM by ROCHE
Source URL:
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Mefloquine, sold under the brand names Lariam among others, is a medication used to for the treatment of mild to moderate acute malaria caused by Mefloquineuine-susceptible strains of Plasmodium falciparum (both chloroquine-susceptible and resistant strains) or by Plasmodium vivax. Also for the prophylaxis of Plasmodium falciparum and Plasmodium vivax malaria infections, including prophylaxis of chloroquine-resistant strains of Plasmodium falciparum. Mefloquine acts as a blood schizonticide. Mefloquine is active against the erythrocytic stages of Plasmodium species. However, the drug has no effect against the exoerythrocytic (hepatic) stages of the parasite. Mefloquine is effective against malaria parasites resistant to chloroquine. Mefloquine is a chiral molecule. According to some research, the (+) enantiomer is more effective in treating malaria, and the (-) enantiomer specifically binds to adenosine receptors in the central nervous system, which may explain some of its psychotropic effects.
