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Details

Stereochemistry ACHIRAL
Molecular Formula C17H27NO3
Molecular Weight 293.4012
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of EMBUTRAMIDE

SMILES

CCC(CC)(CNC(=O)CCCO)C1=CC=CC(OC)=C1

InChI

InChIKey=LMBMDLOSPKIWAP-UHFFFAOYSA-N
InChI=1S/C17H27NO3/c1-4-17(5-2,13-18-16(20)10-7-11-19)14-8-6-9-15(12-14)21-3/h6,8-9,12,19H,4-5,7,10-11,13H2,1-3H3,(H,18,20)

HIDE SMILES / InChI

Description

Embutramide is a veterinary, CNS active medicine used for euthanasia in dogs. The drug is marketed under the name Tributame in the USA and under the name Tanax in Europe. Human consumption of the drug is usually associated with suicide attempts.

CNS Activity

CNS Active
4,002

Originator

Hoechst
44

Approval Year

2006
190

Conditions

ConditionModalityTargetsHighest PhaseProduct
Euthanasia
3
 Palliative
Approved
8,583
TRIBUTAME

PubMed

Patents

20020042381
2

Sample Use Guides

In Vivo Use Guide
Inject 1 mL of embutramide (in the form of TRIBUTAME Euthanasia Solution) for each 5 pounds body weight (0.45 mL/kg). Administer the calculated dose as a single intravenous bolus injection within a 10- to 15 second period.
Route of Administration: Intravenous
In Vitro Use Guide
Unknown
ACTIVE MOIETY
Structure of EMBUTRAMIDE
NIH
NCATS
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