EMBUTRAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H27NO3
Molecular Weight	293.4012
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(CC)(CNC(=O)CCCO)C1=CC(OC)=CC=C1

InChI

InChIKey=LMBMDLOSPKIWAP-UHFFFAOYSA-N

InChI=1S/C17H27NO3/c1-4-17(5-2,13-18-16(20)10-7-11-19)14-8-6-9-15(12-14)21-3/h6,8-9,12,19H,4-5,7,10-11,13H2,1-3H3,(H,18,20)

HIDE SMILES / InChI

Molecular Formula	C17H27NO3
Molecular Weight	293.4012
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.fda.gov/downloads/AnimalVeterinary/Products/ApprovedAnimalDrugProducts/FOIADrugSummaries/ucm051493.pdf
Curator's Comment: description was created based on several sources, including, www.ncbi.nlm.nih.gov/pubmed/27404634

Embutramide is a veterinary, CNS active medicine used for euthanasia in dogs. The drug is marketed under the name Tributame in the USA and under the name Tanax in Europe. Human consumption of the drug is usually associated with suicide attempts.

CNS Activity

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Euthanasia 3 Sources: http://www.fda.gov/downloads/AnimalVeterinary/Products/ApprovedAnimalDrugProducts/FOIADrugSummaries/ucm051493.pdf	Palliative		Approved 8429	TRIBUTAME Approved Use TRIBUTAME Euthanasia Solution is indicated for euthanasia in dogs only. Launch Date 2005

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Inject 1 mL of embutramide (in the form of TRIBUTAME Euthanasia Solution) for each 5 pounds body weight (0.45 mL/kg). Administer the calculated dose as a single intravenous bolus injection within a 10- to 15 second period.

Route of Administration: Intravenous

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:56:31 GMT 2023` Edited by `admin` on `Fri Dec 15 15:56:31 GMT 2023`
Record UNII	3P4TQG94T1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EMBUTRAMIDE

Official Name

English

N-(.BETA.,.BETA.-DIETHYL-M-METHOXYPHENETHYL)-4-HYDROXYBUTYRAMIDE

Systematic Name

English

embutramide [INN]

Common Name

English

EMBUTRAMIDE [USAN]

Common Name

English

EMBUTRAMID [GREEN BOOK]

Common Name

English

HOE-18-680

Code

English

T-61

Code

English

EMBUTRAMIDE [MART.]

Common Name

English

EMBUTRAMID

Common Name

English

HOE-18680

Code

English

EMBUTANE

Code

English

BUTANAMIDE, N-(2-ETHYL-2-(3-METHOXYPHENYL)BUTYL)-4-HYDROXY-

Systematic Name

English

HOE 18 680

Code

English

Classification Tree Code System Code

DEA NO.

2020