U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 158701 - 158710 of 167129 results

Status:
US Previously Marketed
Source:
fructose
(1921)
Source URL:
First marketed in 1921

Class (Stereo):
CHEMICAL (RACEMIC)

Conditions:

Fructose, or fruit sugar, is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose. At a commercial scale, fructose is often derived from sugar cane, sugar beets, and maize. Fructose is one of the three dietary monosaccharides, along with glucose and galactose, that are absorbed directly into the bloodstream. A growing body of research suggests that diet high in fructose may be contributing to incidences of obesity, insulin resistance, and diabetes.
Status:
US Previously Marketed
Source:
Cotarnine Hydrochloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Cotarnine Hydrochloride U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Silver iodide is an inorganic compound with the formula AgI. It is used as a photosensitive agent in photography, as a local antiseptic, as a chemical intermediate, and in cloud seeding for rain-making. The major hazards encountered in the use and handling of silver iodide stem from its toxicologic properties. Effects from exposure may include skin rashes, conjunctivitis, argyria (a permanent ashen-gray discoloration of skin, conjunctiva, and internal organs), headache, fever, hypersensitivity, laryngitis, and bronchitis.
Status:
US Previously Marketed
Source:
Veratrine U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Veratrine U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Cevadine, veratridine, and related lipophilic ceveratrum alkaloids cause activation of the voltage-sensitive Na+ channels of nerve, heart, and skeletal muscle cell membranes similar to pyrethrins. Both veratridine and cevadine alter the ion selectivity of Na+ channels and cause persistent activation. The receptor for these alkaloids has not been isolated, but experiments indicate it is distinct from that of pyrethrin. Structurally, veratridine and cevadine differ only in their acyl group. Cevadine has been used as an insecticide, acting as a paralytic agent with higher toxicity to insects than to mammals. It has been used to study Na+ channel blockers such as vincamine and vincanol by inducing Na+ channels in the presence and absence of the drugs being tested.
Status:
US Previously Marketed
Source:
Pelletierine Tannate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Pelletierine Tannate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Pelletierine is an alkaloid found in the root-bark of the pomegranate tree. There is a little information about the pharmacological application of this compound, but one article describes the anthelminthic activity of pelletierine.
Status:
US Previously Marketed
Source:
Bromauric Acid N. F.
(1921)
Source URL:
First marketed in 1921
Source:
Bromauric Acid N. F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Gold trichloride is used as a catalyst in synthesis of new compounds. It was shown that gold trichloride was not the marker of contact allergy and could not be recommended in patch testing.
Status:
US Previously Marketed
Source:
Antimony Oxide N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Antimony Oxide N.F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)



Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.
Status:
US Previously Marketed
Source:
potassium glutamate
(1921)
Source URL:
First marketed in 1921
Source:
potassium glutamate
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
US Previously Marketed
Source:
NYLMERATE BORIC ACID by HOLLAND-RANTDS
(1961)
Source URL:
First marketed in 1921
Source:
Boric Acid U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

AMMONIUM BORATE is used in fireproofing wood and textiles, and also in electrolytic condensers. It can be indirect additive used in food contact substances.
Glycyrrhizic Acid is specific compound isolated from licorice plants. Ammonium Glycyrrhizate (also known as GLYCYRRHIZIN, AMMONIATED) is a salt, was investigated to be a safe and is used as ingredient in the formulation of makeup, fragrance, hair care, skin care, shaving, personal hygiene and suntan products.

Showing 158701 - 158710 of 167129 results