Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | 5O.2Sb |
| Molecular Weight | 323.517 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[O--].[O--].[O--].[O--].[O--].[Sb+5].[Sb+5]
InChI
InChIKey=HFDPUERWEDZVAU-UHFFFAOYSA-N
InChI=1S/5O.2Sb/q5*-2;2*+5
DescriptionSources: https://www.whocc.no/atcvet/atcvet_index/?code=QR05CA07https://www.ncbi.nlm.nih.gov/pubmed/5295139 | https://www.ncbi.nlm.nih.gov/pubmed/14851220 | https://www.ncbi.nlm.nih.gov/pubmed/8898332Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936
Sources: https://www.whocc.no/atcvet/atcvet_index/?code=QR05CA07https://www.ncbi.nlm.nih.gov/pubmed/5295139 | https://www.ncbi.nlm.nih.gov/pubmed/14851220 | https://www.ncbi.nlm.nih.gov/pubmed/8898332
Curator's Comment: description was created based on several sources, including https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7ef48d40-6d63-440b-a73c-46d89f425936
Stibophen (Fuadin), an organic trivalent antimony compound, has been used for many years in the treatment of schistosomiasis. Stibophen is used as treatment of schistosomiasis by intramuscular injection. Stibophen is known to act by selectively inhibiting worm PFK.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Evaluation of fuadin therapy in schistosomiasis japonica. | 1951 Apr |
|
| Laboratory studies on the joint effects of certain tris (p-aminophenyl) carbonium salts and antimonials as antischistosomal drugs. | 1965 |
|
| Current chemotherapy of schistosomiasis japonica in the Philippines. | 1976 Jun |
|
| [Substantiation of maximum permissible levels of antimony trioxide and pentasulide in the atmospheric air of inhabitated places]. | 1989 Apr |
|
| Purification, kinetics and inhibition by antimonials of recombinant phosphofructokinase from Schistosoma mansoni. | 1996 Oct 30 |
|
| Antimony impairs nucleotide excision repair: XPA and XPE as potential molecular targets. | 2010 Jul 19 |
|
| Investigation on the pharmacological profile of 2,6-diacetylpyridine bis(benzoylhydrazone) derivatives and their antimony(III) and bismuth(III) complexes. | 2012 Jul |
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1314-60-9
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DTXSID6050467
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91617939
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756OCG058B
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Antimony pentoxide
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m1959
Created by
admin on Sat Dec 16 08:42:26 GMT 2023 , Edited by admin on Sat Dec 16 08:42:26 GMT 2023
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PRIMARY | Merck Index |
SUBSTANCE RECORD
