Nitroscanate (trade name Lopatol) is a medium-spectrum anthelmintic used on dogs and cats. It is available in the form of tablets for oral administration. It is not used on livestock. Nitroscanate is effective against the major gastrointestinal roundworms (nematodes) of dogs and cats (e.g.Toxocara canis, Toxocara cati, Ancylostoma spp, Uncinaria stenocephala) and tapeworms (e.g. Dipylidium caninum, Echinococcus granulosus, Taenia spp, etc.). The molecular mode of action of nitroscanate has not been elucidated. It is assumed that it acts as an uncoupler of the oxidative phosphorylation in the cell mitochondria, which disturbs the production of ATP, the cellular "fuel". This impairs the parasites motility and probably other processes as well.

Ttioxidazole has broad spectrum activity against gastrointestinal nematodes. Tiox (tioxidazole) Paste is indicated for removal of mature large strongyles (Strongylus edentatus, S.equinus , and S.vulgaris ), mature ascarids (Parascaris equorum and immature (4th larval stage) pinworms (Oxyuris equi), and mature small strongyles (Triodontophorus spp). Ttioxidazole is a tubulin polymerization inhibitor.

Cambendazole is a veterinary anti-parasitic drug, which was approved by FDA for the treatment of worm infections in horses. The mode of action of cambendazole is the inhibition of glucose uptake, fumarate reductase and phosphoenolpyruvate carboxykinase. Due to its mechanism of action, cambendazole causes the paralysis of parasites.

Buquiterine is an alkaloid useful as antihypertensives and bronchodilators and in the treatment of allergy

Antienite is a highly potent anthelmintic against nematodes in chickens and sheep. Antienite was also active in rodents but it was expensive and had limited solubility in water. These results led the Janssen pharmaceutical company to develop a close analog tetramisole.

Ticarbodine is as effective broad-spectrum canine anthelmintic. Ticarbodine is effective for the ascarids, hookworms, and tapeworms but not the whipworm of dogs. The drug is used in dogs for the removal of roundworms (Toxocara canis), hookworms (Ancylostoma caninum and Uncinaria stenocephala), and tapeworms (Dipylidium caninum and Taenia pisiformis).

Teclozan, an antiprotozoal agent, was used to treat the intestinal amebiasis. Teclozan prevents the formation of arachidonic acid in the parasite by intervening in the phospholipid metabolism.

Bunamidine is a anti-parasitic drug, which was approved by FDA for the treatment of tapeworms in cats and dogs (Scolaban 400 tablets).

Amocarzine is an antifilarial antihelminthic drug, derived from amoscanate, that is active against the adult worms of Onchocerca volvulus. In animal studies of filarial infections, amocarzine showed promise as a macrofilaricidal drug and was afterward extensively tried in humans. Amocrazine has an adverse effects: dizziness, itching and rush. There were reversible neurological symptoms, such as impaired coordination and a positive Romberg’s sign. In a study from Ghana, the combination of ivermectin and amocarzine was not more effective than ivermectine alone and adverse effects were more severe. Amocarzine has no role in the treatment of onchocerciasis in Africa. In silico data emphasize that amocarzine could be potential lead compound that can be further developed into nematicidal chemical against Bursaphelenchus xylophilus.