TECLOZAN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H28Cl4N2O4
Molecular Weight	502.259
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOCCN(CC1=CC=C(CN(CCOCC)C(=O)C(Cl)Cl)C=C1)C(=O)C(Cl)Cl

InChI

InChIKey=MSJLJWCAEPENBL-UHFFFAOYSA-N

InChI=1S/C20H28Cl4N2O4/c1-3-29-11-9-25(19(27)17(21)22)13-15-5-7-16(8-6-15)14-26(10-12-30-4-2)20(28)18(23)24/h5-8,17-18H,3-4,9-14H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/399824 | https://books.google.ru/books?id=b22PDwAAQBAJ&pg=PA141&lpg=PA141&dq=TECLOZAN&source=bl&ots=Hgr30U9gSg&sig=ACfU3U3uvOB6h63aKX2wk3JN_asaDT_8FA&hl=ru&sa=X&ved=2ahUKEwj4__CPtbThAhXwl4sKHaVaCMc4KBDoATAEegQIBxAB#v=onepage&q=TECLOZAN&f=false

Teclozan, an antiprotozoal agent, was used to treat the intestinal amebiasis. Teclozan prevents the formation of arachidonic acid in the parasite by intervening in the phospholipid metabolism.

Approval Year

PubMed

Title	Date	PubMed
Activity of quinfamide against natural infections of Entamoeba criceti in hamsters: a new potent agent for intestinal amoebiasis.	1980-08	6252530
[Treatment of chronic intestinal amebiasis with a single dose of teclozan].	1977-01-01	553463
[Clinical test with teclozan in the treatment of amebic dysentery with a dose of 24 hours].	1977-01-01	399824
[Treatment of intestinal amebiasis with Teclozan].	1972-07-01	4662192

Name

Type

Language

TECLOZAN

Official Name

English

FALMONOX

Preferred Name

English

WIN 13,146

Code

English

NSC-107433

Code

English

teclozan [INN]

Common Name

English

ACETAMIDE, N,N'-(1,4-PHENYLENEBIS(METHYLENE))BIS(2,2-DICHLORO-N-(2-ETHOXYETHYL)-

Systematic Name

English

WIN-13146

Code

English

N,N'-(P-PHENYLENEDIMETHYLENE)BIS(2,2-DICHLORO-N-(2-ETHOXYETHYL)ACETAMIDE)

Common Name

English

TECLOZAN [MART.]

Common Name

English

Teclozan [WHO-DD]

Common Name

English

TECLOZAN [USAN]

Common Name

English

TECLOZAN [MI]

Common Name

English

Classification Tree Code System Code

WHO-ATC

P01AC04