TECLOZAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H28Cl4N2O4
Molecular Weight	502.259
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TECLOZAN

Structure Search

SMILES

CCOCCN(CC1=CC=C(CN(CCOCC)C(=O)C(Cl)Cl)C=C1)C(=O)C(Cl)Cl

InChI

InChIKey=MSJLJWCAEPENBL-UHFFFAOYSA-N

InChI=1S/C20H28Cl4N2O4/c1-3-29-11-9-25(19(27)17(21)22)13-15-5-7-16(8-6-15)14-26(10-12-30-4-2)20(28)18(23)24/h5-8,17-18H,3-4,9-14H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/399824 | https://books.google.ru/books?id=b22PDwAAQBAJ&pg=PA141&lpg=PA141&dq=TECLOZAN&source=bl&ots=Hgr30U9gSg&sig=ACfU3U3uvOB6h63aKX2wk3JN_asaDT_8FA&hl=ru&sa=X&ved=2ahUKEwj4__CPtbThAhXwl4sKHaVaCMc4KBDoATAEegQIBxAB#v=onepage&q=TECLOZAN&f=false

Teclozan, an antiprotozoal agent, was used to treat the intestinal amebiasis. Teclozan prevents the formation of arachidonic acid in the parasite by intervening in the phospholipid metabolism.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Treatment of intestinal amebiasis with Teclozan].	1972 Jul-Dec	4662192
[Treatment of chronic intestinal amebiasis with a single dose of teclozan].	1977-1978	553463
Activity of quinfamide against natural infections of Entamoeba criceti in hamsters: a new potent agent for intestinal amoebiasis.	1980 Aug	6252530

Name

Type

Language

TECLOZAN

Official Name

English

WIN 13,146

Code

English

NSC-107433

Code

English

teclozan [INN]

Common Name

English

ACETAMIDE, N,N'-(1,4-PHENYLENEBIS(METHYLENE))BIS(2,2-DICHLORO-N-(2-ETHOXYETHYL)-

Systematic Name

English

WIN-13146

Code

English

N,N'-(P-PHENYLENEDIMETHYLENE)BIS(2,2-DICHLORO-N-(2-ETHOXYETHYL)ACETAMIDE)

Common Name

English

FALMONOX

Brand Name

English

TECLOZAN [MART.]

Common Name

English

Teclozan [WHO-DD]

Common Name

English

TECLOZAN [USAN]

Common Name

English

TECLOZAN [MI]

Common Name

English

Classification Tree Code System Code

WHO-ATC

P01AC04

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

NCI_THESAURUS

C277

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

Code System Code Type Description

DRUG BANK

DB13205

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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NSC

107433

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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DRUG CENTRAL

2576

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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FDA UNII

K9RIF0COUB

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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WIKIPEDIA

TECLOZAN

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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MERCK INDEX

m10512

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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Merck Index

EVMPD

SUB10863MIG

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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ChEMBL

CHEMBL1788387

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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NCI_THESAURUS

C152533

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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EPA CompTox

DTXSID00204147

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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PUBCHEM

21723

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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SMS_ID

100000082457

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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ECHA (EC/EINECS)

226-934-0

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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CAS

5560-78-1

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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INN

1485

Created by admin on Fri Dec 15 18:55:45 UTC 2023 , Edited by admin on Fri Dec 15 18:55:45 UTC 2023

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ACTIVE MOIETY


					K9RIF0COUB

TECLOZAN