Search results for "Pharmacologic Substance[C1909]|Anti-Infective Agent[C254]|Antiparasitic Agent[C276]" in comments (approximate match)
Class (Stereo):
CHEMICAL (RACEMIC)
PR-69 (Doranidazole) is a hypoxic radiosensitizer, and is a derivative of 2-nitroimidazole intended to reduce neurotoxicity due to its blood brain barrier (BBB) impermeability. Several studies have shown that doranidazole has a radiosensitizing effec...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Kainic acid (kainate) is a natural marine acid present in some seaweed. Kainic acid is a potent neuroexcitatory amino acid that acts by activating receptors for glutamate, the principal excitatory neurotransmitter in the central nervous system. Kaini...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Quinafimide is an investigational compound that has been used in trials for the treatment of Amoebiasis and Helminthiasis. This phase 4 trial combined Quinfamide with the approved compound Mebendazole. The details of the mechanism of action are not...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Piperaquine is a bisquinoline antimalarial drug that was first synthesized in the 1960s and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of...
Clefamide is an aromatic ether and antiprotozoal agent that was used to treat and chemoprophylaxis of amoebiasis in the 1960s
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Eprinomectin is 4"-deoxy-4"-epiacetylamino-avermectin B1. It is a semi-synthetic member of the avermectin family of macrocyclic lactones and consists of a mixture of two homologous components, B1a (not less than 90%) and B1b (not more than 10%), whic...
Arteflene is the sesquiterpene peroxide. It is a synthetic derivative of yingzhaosuwas. Arteflene found negative in a battery of mutagenicity tests. It had low acute toxicity after oral or subcutaneous administration in pre-clinical studies. Experime...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Oxantel is a narrow-spectrum anthelmintic effective against whipworms in dogs and cats. It is ineffective against other roundworms, flukes, tapeworms or external parasites. Oxantel acts on the nervous system of the worms as inhibitors of acetylcholin...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Oxyclozanide is a salicylanilide anthelmintic, used for the treatment and control of fascioliasis in cattle, sheep, and goats. The mechanism of action of oxyclozanide is the uncoupling of oxidative phosphorylation in flukes. It is formulated as an or...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Ipronidazole is an antiprotozoal drug of the nitroimidazole class used in veterinary medicine. Ipronidazole (2-isopropyl-1-methyl-5-nitroimidazole) is used for the treatment of histomoniasis in turkeys and in swine dysentery.