Details
Stereochemistry | MIXED |
Molecular Formula | C15H19F3N2S |
Molecular Weight | 316.385 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 0 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1CCCC(C)N1C(=S)NC2=CC(=CC=C2)C(F)(F)F
InChI
InChIKey=YTNJAWMNFLIDLW-UHFFFAOYSA-N
InChI=1S/C15H19F3N2S/c1-10-5-3-6-11(2)20(10)14(21)19-13-8-4-7-12(9-13)15(16,17)18/h4,7-11H,3,5-6H2,1-2H3,(H,19,21)
Ticarbodine is as effective broad-spectrum
canine anthelmintic. Ticarbodine is effective for the ascarids, hookworms, and tapeworms but not the whipworm of dogs. The drug is used in dogs for the removal of roundworms (Toxocara canis), hookworms (Ancylostoma caninum and Uncinaria stenocephala), and tapeworms (Dipylidium caninum and Taenia
pisiformis).
Originator
Sources: http://www.drugfuture.com/chemdata/ticarbodine.html | https://www.fda.gov/OHRMS/DOCKETS/98fr/cv00141.pdf
Curator's Comment: # Elanco Animal Health, A Div. of Eli Lilly & Co.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: Toxocara canis |
|||
Target ID: CHEMBL612340 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Curative | Ticarbodine Approved UseThe drug is
used in dogs for the removal of
roundworms (Toxocara canis),
hookworms (Ancylostoma caninum and
Uncinaria stenocephala), and tapeworms
(Dipylidium caninum and Taenia
pisiformis). |
PubMed
Title | Date | PubMed |
---|---|---|
Efficacy of single oral doses of ticarbodine against nematodes and cestodes of dogs. | 1972 Apr |
|
Critical and clinical evaluation of ticarbodine as a canine anthelmintic. | 1972 May |
|
In vitro activity of various anthelmintic compounds against Haemonchus contortus larvae. | 1983 Nov |
Patents
Sample Use Guides
Dogs: Dosage is administered at 45 milligrams
of the drug per pound of body
weight in a single dose. Dosage may be
repeated in 21 days
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6686387
Ticarbodine was active against Haemonchus contortus at a concentration of 100 ug/ cm(-3) or less.
Name | Type | Language | ||
---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English |
Classification Tree | Code System | Code | ||
---|---|---|---|---|
|
NCI_THESAURUS |
C250
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
C003469
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
100000082186
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
CHEMBL2104761
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
3023
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
DTXSID40865615
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
SUB11026MIG
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
m966
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | Merck Index | ||
|
31932-09-9
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
C75234
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
J4CLF34O60
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY | |||
|
3034015
Created by
admin on Sat Dec 16 15:54:35 GMT 2023 , Edited by admin on Sat Dec 16 15:54:35 GMT 2023
|
PRIMARY |
ACTIVE MOIETY