TECLOZAN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H28Cl4N2O4
Molecular Weight	502.259
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOCCN(CC1=CC=C(CN(CCOCC)C(=O)C(Cl)Cl)C=C1)C(=O)C(Cl)Cl

InChI

InChIKey=MSJLJWCAEPENBL-UHFFFAOYSA-N

InChI=1S/C20H28Cl4N2O4/c1-3-29-11-9-25(19(27)17(21)22)13-15-5-7-16(8-6-15)14-26(10-12-30-4-2)20(28)18(23)24/h5-8,17-18H,3-4,9-14H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H28Cl4N2O4
Molecular Weight	502.259
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/399824 | https://books.google.ru/books?id=b22PDwAAQBAJ&pg=PA141&lpg=PA141&dq=TECLOZAN&source=bl&ots=Hgr30U9gSg&sig=ACfU3U3uvOB6h63aKX2wk3JN_asaDT_8FA&hl=ru&sa=X&ved=2ahUKEwj4__CPtbThAhXwl4sKHaVaCMc4KBDoATAEegQIBxAB#v=onepage&q=TECLOZAN&f=false

Teclozan, an antiprotozoal agent, was used to treat the intestinal amebiasis. Teclozan prevents the formation of arachidonic acid in the parasite by intervening in the phospholipid metabolism.

Approval Year

PubMed

Title	Date	PubMed
[Treatment of intestinal amebiasis with Teclozan].	1972 Jul-Dec	4662192
[Treatment of chronic intestinal amebiasis with a single dose of teclozan].	1977-1978	553463
[Clinical test with teclozan in the treatment of amebic dysentery with a dose of 24 hours].	1977-1978	399824
Activity of quinfamide against natural infections of Entamoeba criceti in hamsters: a new potent agent for intestinal amoebiasis.	1980 Aug	6252530

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:55:45 GMT 2023` Edited by `admin` on `Fri Dec 15 18:55:45 GMT 2023`
Record UNII	K9RIF0COUB
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TECLOZAN

Official Name

English

WIN 13,146

Code

English

NSC-107433

Code

English

teclozan [INN]

Common Name

English

ACETAMIDE, N,N'-(1,4-PHENYLENEBIS(METHYLENE))BIS(2,2-DICHLORO-N-(2-ETHOXYETHYL)-

Systematic Name

English

WIN-13146

Code

English

N,N'-(P-PHENYLENEDIMETHYLENE)BIS(2,2-DICHLORO-N-(2-ETHOXYETHYL)ACETAMIDE)

Common Name

English

FALMONOX

Brand Name

English

TECLOZAN [MART.]

Common Name

English

Teclozan [WHO-DD]

Common Name

English

TECLOZAN [USAN]

Common Name

English

TECLOZAN [MI]

Common Name

English

Classification Tree Code System Code

WHO-ATC

P01AC04