U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 121 - 130 of 3210 results

Status:
US Animal Drug
Source:
GREEN BOOK:FLUMETHASONE ACETATE [GREEN BOOK]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Conditions:

Flumethasone 21-acetate is an anti-inflammatory corticosteroid. It has 300 times greater anti-inflammatory activity and 677 times greater capacity to promote liver glycogen deposition than hydrocortisone. It has anti-rheumatic potency 31 times higher than cortisol.
Status:
Investigational
Source:
INN:upleganan [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:aroxybutynin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:resomelagon [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
Investigational
Source:
INN:gadoquatrane [INN]
Source URL:

Class (Stereo):
CHEMICAL (MIXED)

Status:
Investigational
Source:
INN:lefleuganan [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Status:
Investigational
Source:
INN:cormetasone
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)

Cormethasone is a topical antiinflammatory corticosteroid discovered by Du Pont.
Status:
Investigational
Source:
INN:talmetacin
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Talmetacin is a cyclo-oxygenase inhibitor that was studied as an analgesic and antipyretic agent. This drug was studied in Argentina in patients with rheumatic disorders. However, further development of talmetacin is not available.
Status:
Investigational
Source:
INN:sarsagenin [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)


PYM50018 (also known as Myogane or SARSAGENIN) has demonstrated neuroprotective effects in several preclinical models. It was observed that PYM50018 protects against neuronal damage, increases neurite outgrowth, reverses oxidative damage and reversed neuronal apoptosis. PYM50018 is in phase I clinical study for the treatment of amyotrophic lateral sclerosis (ALS).
Status:
Investigational
Source:
INN:amibegron [INN]
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Amibegron (SR 58611A or SR 58611) is a highly selective agonist for atypical beta3-adrenoceptors. It stimulates neuronal activity in a specific area of the prefrontal cortex and also inhibits intestinal motility. Amibegron was in phase III trials worldwide for the treatment of depression and generalised anxiety disorder but development of the product was discontinued in 2008. Amibegron has been tested for its potential as a treatment for irritable bowel syndrome.