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Showing 1 - 10 of 112 results

Status:
US Approved Rx (2022)
First approved in 2006

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

Lubiprostone is a medication used in the management of idiopathic chronic constipation. It is a bicyclic fatty acid (prostaglandin E1 derivative) which acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal e...
Status:
US Approved Rx (2017)
First approved in 1971

Class (Stereo):
CHEMICAL (ABSOLUTE)



Naloxone, sold under the brand name Narcan among others, is a medication used to block the effects of opioids, especially in overdose. Naloxone has an extremely high affinity for μ-opioid receptors in the central nervous system (CNS). Naloxone is a μ...
Status:
US Approved Rx (2020)
First approved in 1955

Class (Stereo):
CHEMICAL (ACHIRAL)


Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including ...
Status:
US Approved Rx (2020)
First approved in 1955

Class (Stereo):
CHEMICAL (ABSOLUTE)


Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including ...
Status:
US Approved Rx (2020)
First approved in 1955

Class (Stereo):
CHEMICAL (ABSOLUTE)


Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including ...
Status:
US Approved Rx (2020)
First approved in 1953

Class (Stereo):
CHEMICAL (ABSOLUTE)


Lactitol is a sugar alcohol. This ingredient has been determined to be GRAS for specified uses as a direct food additive and foods containing lactitol are eligible for a health claim related to dental caries. Lactitol is used as an oral powder or sol...
Status:
US Approved OTC
First marketed in 1921

Class (Stereo):
CHEMICAL (ACHIRAL)



Struvite, a crystalline substance first identified in the 18th century, is composed of magnesium ammonium phosphate. Struvite urinary stones are also known as ‘infection stones’, and account for 15%-20% of all urinary stones. Bacterial urease, usuall...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Pumosetrag is a novel, orally active and selective 5-HT 3 agonist. It is a partial agonist in rats and guinea-pig and a full agonist in the mouse, suggesting important species differences in 5-HT3 receptor structure. Pumosetrag had been in phase II c...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Velusetrag (TD-5108) is a potent, selective high intrinsic activity serotonin 5-HT(4) receptor agonist. Velusetrag has achieved proof-of-concept in patients with chronic idiopathic constipation and was on phase II of clinical trial for the treatment ...
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Thymolphthalein is a weak organic acid that behaves as an acid-base indicator in the pH range 9.3 (colorless) to 10.5 (blue). Thymolphthalein is also known to have been used as a laxative and for disappearing ink.