Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Topiramate is an anticonvulsant indicated in the treatment of epilepsy and migraine. Topiramate enhances GABA-activated chloride channels. In addition, topiramate inhibits excitatory neurotransmission, through actions on kainate and AMPA receptors. T...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Indapamide is an antihypertensive and a diuretic. It contains both a polar sulfamoyl chlorobenzamide moiety and a lipid- soluble methylindoline moiety. Indapamide blocks the slow component of delayed rectifier potassium current (IKs) without altering...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
Methazolamide is topical carbonic anhydrase inhibitor. Methazolamide is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers. Metha...
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Acetazolamide, usually sold under the trade name Diamox in some countries. DIAMOX is used for adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery...
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Sulfasuccinamide is a sulfonamide antibacterial with properties
similar to those of sulfamethoxazole. It has been applied
topically in the treatment of local infections of the ear, nose, and
throat. It has also been given as the sodium salt. Sulfasuc...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets:
Conditions:
U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces ...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Other
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Cortex fraxini, a famous Chinese herbal folk medicine, is used for the
clinical treatment of hyperuricemia, arthritis, diarrhea, liver-protective. and bacillary dysentery. Fraxin, a main active component isolated from Cortex fraxini, possesses a vari...
Status:
Other
Class (Stereo):
CHEMICAL (ACHIRAL)
Targets: