CHLORAMINOPHENAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H8ClN3O4S2
Molecular Weight	285.728
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=C(C=C(C(Cl)=C1)S(N)(=O)=O)S(N)(=O)=O

InChI

InChIKey=IHJCXVZDYSXXFT-UHFFFAOYSA-N

InChI=1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14)

HIDE SMILES / InChI

Molecular Formula	C6H8ClN3O4S2
Molecular Weight	285.728
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
Carbonic anhydrase II 88 Target ID: CHEMBL205 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15482952 \| https://patents.google.com/patent/US9670186	Inhibitor 8228	96.0 nM [IC50]
Carbonic anhydrase VA 27 Target ID: CHEMBL4789 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15482952 \| https://patents.google.com/patent/US9670186	Inhibitor 8228	4.17 µM [IC50]
Carbonic anhydrase XII 30 Target ID: CHEMBL3242 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16039848	Inhibitor 8228	44.0 nM [Ki]
Carbonic anhydrase IX 37 Target ID: CHEMBL3594 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16039848	Inhibitor 8228	39.0 nM [Ki]

PubMed

Title	Date	PubMed
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.	2006 Apr 15	16459077
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.	2006 Mar 23	16539401
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.	2007 Dec 1	17826101

Substance Class	Chemical Created by `admin` on `Thu Jul 06 10:10:34 UTC 2023` Edited by `admin` on `Thu Jul 06 10:10:34 UTC 2023`
Record UNII	3A52O8YREJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHLORAMINOPHENAMIDE

Common Name

English

CHLOROAMINOPHENAMIDE

Common Name

English

4-AMINO-6-CHLOROBENZENE-1,3-DISULPHONAMIDE

Systematic Name

English

SALAMIDE

Common Name

English

CHLORAMINOPHENAMIDE [MI]

Common Name

English

2-AMINO-4-CHLORO-M-BENZENEDISULFONAMIDE

Common Name

English

3-CHLORO-4,6-DISULFAMOYLANILINE

Systematic Name

English

SALAMID

Common Name

English

NSC-93772

Code

English

SU-5683

Code

English

1-AMINO-5-CHLORO-2,4-BENZENEDISULFONAMIDE

Systematic Name

English

HYDROCHLOROTHIAZIDE IMPURITY B [EP IMPURITY]

Common Name

English

M-BENZENEDISULFONAMIDE, 4-AMINO-6-CHLORO-

Common Name

English

IDORESE

Common Name

English

5-CHLORO-2,4-DISULFAMOYLANILINE

Systematic Name

English

BENZOTHIADIAZINE RELATED COMPOUND A [USP-RS]

Common Name

English

1,3-BENZENEDISULFONAMIDE, 4-AMINO-6-CHLORO-

Systematic Name

English

4-AMINO-6-CHLORO-1,3-BENZENEDISULFONAMIDE

Systematic Name

English

ALTIZIDE IMPURITY A [EP IMPURITY]

Common Name

English

BENZOTHIADIAZINE RELATED COMPOUND A [USP IMPURITY]

Common Name

English

Code System Code Type Description

CAS

121-30-2