U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H8ClN3O4S2
Molecular Weight 285.7308
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHLORAMINOPHENAMIDE

SMILES

c1c(c(cc(c1N)S(=O)(=O)N)S(=O)(=O)N)Cl

InChI

InChIKey=IHJCXVZDYSXXFT-UHFFFAOYSA-N
InChI=1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14)

HIDE SMILES / InChI

Molecular Formula C6H8ClN3O4S2
Molecular Weight 285.7308
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Isolation of a 2:1 hydrochlorothiazide-formaldehyde adduct impurity in hydrochlorothiazide drug substance by preparative chromatography and characterization by electrospray ionization LC-MS.
2001 Nov
Mass spectrometric behavior of thiazide-based diuretics after electrospray ionization and collision-induced dissociation.
2002 Aug 1
Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.
2006 Apr 15
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.
2006 Mar 23
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.
2007 Dec 1
Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.
2009 Apr
Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis.
2009 Mar 20
Substance Class Chemical
Created
by admin
on Sat Jun 26 11:11:54 UTC 2021
Edited
by admin
on Sat Jun 26 11:11:54 UTC 2021
Record UNII
3A52O8YREJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHLORAMINOPHENAMIDE
MI  
Common Name English
CHLOROAMINOPHENAMIDE
Common Name English
4-AMINO-6-CHLOROBENZENE-1,3-DISULPHONAMIDE
Systematic Name English
BENZOTHIADIAZINE RELATED COMPOUND A [USP]
Common Name English
HYDROCHLOROTHIAZIDE SPECIFIED IMPURITY B [EP]
Common Name English
SALAMIDE
Common Name English
CHLORAMINOPHENAMIDE [MI]
Common Name English
2-AMINO-4-CHLORO-M-BENZENEDISULFONAMIDE
Common Name English
3-CHLORO-4,6-DISULFAMOYLANILINE
Systematic Name English
SALAMID
Common Name English
NSC-93772
Code English
SU-5683
Code English
1-AMINO-5-CHLORO-2,4-BENZENEDISULFONAMIDE
Systematic Name English
ALTIZIDE IMPURITY A [EP]
Common Name English
M-BENZENEDISULFONAMIDE, 4-AMINO-6-CHLORO-
Common Name English
IDORESE
Common Name English
5-CHLORO-2,4-DISULFAMOYLANILINE
Systematic Name English
BENZOTHIADIAZINE RELATED COMPOUND A [USP-RS]
Common Name English
1,3-BENZENEDISULFONAMIDE, 4-AMINO-6-CHLORO-
Systematic Name English
BENZOTHIADIAZINE RELATED COMPOUND A
USP   USP-RS  
Common Name English
4-AMINO-6-CHLORO-1,3-BENZENEDISULFONAMIDE
Systematic Name English
Code System Code Type Description
CAS
121-30-2
Created by admin on Sat Jun 26 11:11:55 UTC 2021 , Edited by admin on Sat Jun 26 11:11:55 UTC 2021
PRIMARY
MERCK INDEX
M3346
Created by admin on Sat Jun 26 11:11:55 UTC 2021 , Edited by admin on Sat Jun 26 11:11:55 UTC 2021
PRIMARY Merck Index
PUBCHEM
67136
Created by admin on Sat Jun 26 11:11:55 UTC 2021 , Edited by admin on Sat Jun 26 11:11:55 UTC 2021
PRIMARY
USP_CATALOG
1057507
Created by admin on Sat Jun 26 11:11:55 UTC 2021 , Edited by admin on Sat Jun 26 11:11:55 UTC 2021
PRIMARY USP-RS
FDA UNII
3A52O8YREJ
Created by admin on Sat Jun 26 11:11:55 UTC 2021 , Edited by admin on Sat Jun 26 11:11:55 UTC 2021
PRIMARY
EPA CompTox
121-30-2
Created by admin on Sat Jun 26 11:11:55 UTC 2021 , Edited by admin on Sat Jun 26 11:11:55 UTC 2021
PRIMARY
ECHA (EC/EINECS)
204-463-1
Created by admin on Sat Jun 26 11:11:55 UTC 2021 , Edited by admin on Sat Jun 26 11:11:55 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> DEGRADENT
PARENT -> DERIVATIVE
Related Record Type Details
PARENT -> METABOLITE
Related Record Type Details
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP