CHLORAMINOPHENAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H8ClN3O4S2
Molecular Weight	285.728
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=C(C=C(C(Cl)=C1)S(N)(=O)=O)S(N)(=O)=O

InChI

InChIKey=IHJCXVZDYSXXFT-UHFFFAOYSA-N

InChI=1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14)

HIDE SMILES / InChI

Molecular Formula	C6H8ClN3O4S2
Molecular Weight	285.728
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Potency
Carbonic anhydrase II 88 Target ID: CHEMBL205 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15482952 \| https://patents.google.com/patent/US9670186	Inhibitor 8297	96.0 nM [IC50]
Carbonic anhydrase VA 25 Target ID: CHEMBL4789 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15482952 \| https://patents.google.com/patent/US9670186	Inhibitor 8297	4.17 µM [IC50]
Carbonic anhydrase XII 30 Target ID: CHEMBL3242 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16039848	Inhibitor 8297	44.0 nM [Ki]
Carbonic anhydrase IX 35 Target ID: CHEMBL3594 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16039848	Inhibitor 8297	39.0 nM [Ki]

PubMed

Title	Date	PubMed
Mass spectrometric behavior of thiazide-based diuretics after electrospray ionization and collision-induced dissociation.	2002 Aug 1	12175169
Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.	2009 Apr	18608752
Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis.	2009 Mar 20	19187939

Substance Class	Chemical Created by `admin` on `Sat Dec 16 04:14:42 GMT 2023` Edited by `admin` on `Sat Dec 16 04:14:42 GMT 2023`
Record UNII	3A52O8YREJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHLORAMINOPHENAMIDE

Common Name

English

CHLOROAMINOPHENAMIDE

Common Name

English

4-AMINO-6-CHLOROBENZENE-1,3-DISULPHONAMIDE

Systematic Name

English

SALAMIDE

Common Name

English

CHLORAMINOPHENAMIDE [MI]

Common Name

English

2-AMINO-4-CHLORO-M-BENZENEDISULFONAMIDE

Common Name

English

3-CHLORO-4,6-DISULFAMOYLANILINE

Systematic Name

English

SALAMID

Common Name

English

NSC-93772

Code

English

SU-5683

Code

English

1-AMINO-5-CHLORO-2,4-BENZENEDISULFONAMIDE

Systematic Name

English

HYDROCHLOROTHIAZIDE IMPURITY B [EP IMPURITY]

Common Name

English

M-BENZENEDISULFONAMIDE, 4-AMINO-6-CHLORO-

Common Name

English

IDORESE

Common Name

English

5-CHLORO-2,4-DISULFAMOYLANILINE

Systematic Name

English

BENZOTHIADIAZINE RELATED COMPOUND A [USP-RS]

Common Name

English

1,3-BENZENEDISULFONAMIDE, 4-AMINO-6-CHLORO-

Systematic Name

English

4-AMINO-6-CHLORO-1,3-BENZENEDISULFONAMIDE

Systematic Name

English

ALTIZIDE IMPURITY A [EP IMPURITY]

Common Name

English

BENZOTHIADIAZINE RELATED COMPOUND A [USP IMPURITY]

Common Name

English

Code System Code Type Description

CAS

121-30-2