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Showing 1 - 10 of 70 results

Status:
US Approved Rx (2009)
First approved in 2009

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Iloperidone, also known as Fanapt, Fanapta, and previously known as Zomaril, is an atypical antipsychotic for the treatment of schizophrenia. Iloperidone shows high affinity and maximal receptor occupancy for dopamine D2 receptors in the caudate nucl...
Status:
US Approved Rx (2023)
First approved in 1986

Class (Stereo):
CHEMICAL (ACHIRAL)



Etiguanfacine, also known as SSP-1871, is an α2-adrenoreceptor agonist.
Status:
US Approved Rx (1987)
First approved in 1974

Class (Stereo):
CHEMICAL (ACHIRAL)



Clonidine is a centrally acting α2 adrenergic agonist and imidazoline receptor agonist used to treat high blood pressure, attention deficit hyperactivity disorder, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking...
Status:
US Approved Rx (2021)
First approved in 1950

Class (Stereo):
CHEMICAL (ABSOLUTE)



Norepinephrine (l-arterenol/Levarterenol or l-norepinephrine) is a sympathomimetic catecholamine with multiple roles including as a hormone and a neurotransmitter. As a stress hormone, norepinephrine affects parts of the brain where attention and res...
Status:
US Approved OTC
First approved in 2003

Class (Stereo):
CHEMICAL (ACHIRAL)



A sulfide ion is composed of a lone sulfur atom. Its charge is negative two, giving sulfides this formula: S^2-. Sulfide is a strong base, so solutions of sulfide in water are basic, due to hydrolysis. One well-known ionic compound with a sulfide ion...
Status:
US Approved OTC
First approved in 1964

Class (Stereo):
CHEMICAL (ACHIRAL)



Oxymetazoline is an adrenergic alpha-agonist, direct acting sympathomimetic, used as a vasoconstrictor to relieve nasal congestion The sympathomimetic action of oxymetazoline constricts the smaller arterioles of the nasal passages, producing a prolon...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)



The aluminum salt of Allantoin, Alcloxa combines the astringent and anti-microbial properties of aluminum with the anti-irritant, soothing and healing properties of Allantoin. Alcloxa is particularly suited for use in anti-perspirants, acne treatment...
Status:
Investigational

Class (Stereo):
CHEMICAL (ABSOLUTE)



Conessine is a plant steroid alkaloid that acts as a potent and specific antagonist of histamine H3 receptors. Conessine displayed high affinity at both rat and human H3 receptors (pKi = 7.61 and 8.27) and generally high selectivity against other sit...
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)


Efaroxan (RX 821037) is a potent and selective alpha(2)-adrenoceptor antagonist. Additionally, Efaroxan is a selective antagonist at the imidazoline I1 receptor. Efaroxan promotes insulin secretion, in the absence of exogenous agonists, by a mechanis...
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)



Idazoxan is an alpha2 receptor antagonist which also shows activity at imidazoline I1 and I2 receptors and modulates the release of dopamine. Idazoxan was in phase II development in the US. Later the development of idazoxan for schizophrenia was disc...