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Details

Stereochemistry RACEMIC
Molecular Formula C4H6N4O3
Molecular Weight 158.1156
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALLANTOIN

SMILES

C1(C(=NC(=N1)O)O)NC(=N)O

InChI

InChIKey=POJWUDADGALRAB-UHFFFAOYSA-N
InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)

HIDE SMILES / InChI

Molecular Formula C4H6N4O3
Molecular Weight 158.1156
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

The aluminum salt of Allantoin, Alcloxa combines the astringent and anti-microbial properties of aluminum with the anti-irritant, soothing and healing properties of Allantoin. Alcloxa is particularly suited for use in anti-perspirants, acne treatments and foot care products. Alcloxa is a compound that combine the properties of aluminum salts with the properties of allantion. The allantion component ehhances the action of the aluminum salts and serves to overcome irritations experienced by many individuals who may be sensitive to the use of aluminum alts. The aluminum component reduces sweat by causing the sweat gland ducts swell. Alcloxa also add to the antiperspirant properties the deodorant effect because of its bacteriostatic action. It showed bacteriostatic properties at concentrations of 0.2% particularly against Gram + bectaria (B. subtilis, S. aureus, P. vulgaris, Pityrosporum ovale). This is ascribable to two different mechanisms: first bacterial growth is retarded due to a decrease in the amount of water present, second aluminum salt have itself an antimicrobial action. In baby products is indicated for its healing reparative action, in the treatment of diaper rash. Also is approved in haemorrhoidal product for its soothing and keratolytic action. In oral care products Alcloxa is useful for its astringent antibacterial properties. It is very indicated in formulations for sensitive teeth, periodontal and gum diseases (like gingivitis, irritable and bleeding gums). Use levels: 0.1-1%. − In antiacne products the slightly astringent effect promotes healing of pustules and acne lesions. It reduces the extension of infected skin eruptions, healing them and developing a soothing action. May be used alone or also in combinations with other antimicrobial agents in order to fight acne more effectively. Use levels: 0.5-2.0%.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
BODYGLIDE FOR HER

Approved Use

helps prevent and helps relieve chafed, chapped or cracked skin. helps protect from the drying effects of wind and cold weather. temporarily protects minor cuts, scrapes, burns.

Launch Date

1.25902075E12
Primary
Unknown

Approved Use

Unknown
Primary
Unknown

Approved Use

protects gastric / duodenal tissue mucosa and helps repair, thus improving gastric / duodenal ulcer and gastritis. It is usually used to improve subjective symptoms or objective of gastric/duodenal ulcer and gastritis.
Primary
Unknown

Approved Use

protects gastric / duodenal tissue mucosa and helps repair, thus improving gastric / duodenal ulcer and gastritis. It is usually used to improve subjective symptoms or objective of gastric/duodenal ulcer and gastritis.
Primary
Unknown

Approved Use

protects gastric / duodenal tissue mucosa and helps repair, thus improving gastric / duodenal ulcer and gastritis. It is usually used to improve subjective symptoms or objective of gastric/duodenal ulcer and gastritis.
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
6.43 μg/mL
10 mg/kg 3 times / day steady-state, oral
dose: 10 mg/kg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ALLANTOIN plasma
Canis lupus
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
30 μg × h/mL
10 mg/kg 3 times / day steady-state, oral
dose: 10 mg/kg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ALLANTOIN plasma
Canis lupus
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
2.69 h
10 mg/kg 3 times / day steady-state, oral
dose: 10 mg/kg
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
ALLANTOIN plasma
Canis lupus
population: HEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

In general, for adults, take 3 to 4 tablets (300 to 400 mg of the active ingredient) a day, in 3 to 4 divided doses.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Jun 25 20:57:00 UTC 2021
Edited
by admin
on Fri Jun 25 20:57:00 UTC 2021
Record UNII
344S277G0Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALLANTOIN
EP   HSDB   II   INCI   JAN   MART.   MI   USAN   USP   USP-RS   VANDF   WHO-DD  
INCI   USAN  
Official Name English
IDELALISIB METABOLITE M1A
Common Name English
ALLANTOIN [INCI]
Common Name English
ALLANTOIN [USP MONOGRAPH]
Common Name English
CORDIANINE
Common Name English
NSC-7606
Code English
PSORALON
Common Name English
ALWEXTIN
Brand Name English
ALLANTOIN [MART.]
Common Name English
(2,5-DIOXO-4-IMIDAZOLIDINYL)UREA
Systematic Name English
ALLANTOIN [HSDB]
Common Name English
ALLANTOIN [VANDF]
Common Name English
(+/-)-ALLANTOIN
Common Name English
ALLANTOIN [II]
Common Name English
SD 101 [WHO-DD]
Common Name English
ALLANTOIN [MI]
Common Name English
ALLANTOIN [JAN]
Common Name English
UREA, (2,5-DIOXO-4-IMIDAZOLIDINYL)-
Systematic Name English
ALLANTOIN [USAN]
Common Name English
5-UREIDOHYDANTOIN
Systematic Name English
DL-ALLANTOIN
Common Name English
ALLANTOIN [WHO-DD]
Common Name English
SEPTALAN
Common Name English
ALLANTOIN [USP-RS]
Common Name English
ALLANTOIN [EP MONOGRAPH]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C29700
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
CFR 21 CFR 347.10
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
DSLD 3892 (Number of products:4)
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
CFR 21 CFR 310.534
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
EU-Orphan Drug EU/3/13/1232
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
NCI_THESAURUS C29708
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
EPA PESTICIDE CODE 85701
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
FDA ORPHAN DRUG 151001
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
Code System Code Type Description
DRUG BANK
DB11100
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
DRUG CENTRAL
4268
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
NCI_THESAURUS
C74277
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
HSDB
7490
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
WIKIPEDIA
ALLANTOIN
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
EPA CompTox
97-59-6
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
ECHA (EC/EINECS)
202-592-8
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
FDA UNII
344S277G0Z
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
EVMPD
SUB12779MIG
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
ChEMBL
CHEMBL593429
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
PUBCHEM
204
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
CAS
97-59-6
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
USP_CATALOG
1012939
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY USP-RS
MERCK INDEX
M1520
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY Merck Index
MESH
D000481
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY
RXCUI
508
Created by admin on Fri Jun 25 20:57:00 UTC 2021 , Edited by admin on Fri Jun 25 20:57:00 UTC 2021
PRIMARY RxNorm
Related Record Type Details
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ACTIVE MOIETY