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Showing 1 - 10 of 46 results

Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)



The aluminum salt of Allantoin, Alcloxa combines the astringent and anti-microbial properties of aluminum with the anti-irritant, soothing and healing properties of Allantoin. Alcloxa is particularly suited for use in anti-perspirants, acne treatment...
Status:
US Approved OTC
First approved in 1961

Class (Stereo):
CHEMICAL (ACHIRAL)



Bismuth aluminate is an antacid drug. The good therapeutic results are due to a coating effect providing a local antipepsin action at the site of the ulcer is an interesting possibility. Inorganic bismuth derivatives have good antibacterial propertie...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)



Esaprazole, also known as hexaprazole, was developed in the 1980s as a drug for the treatment of gastric and duodenal ulcers. Esaprazole exerts a dose-dependent cytoprotective effect on the gastric mucosa in man. It was shown to have a dose-dependent...
Status:
Investigational

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Butinoline (also known as azulone) was used as an antispasmodic drug to treat gastritis.
Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Iridoid glycoside gardenoside is the main effective extraction of Gardenia jasminoides Ellis, which is an indigenous medicinal herb widely used for hepatoprotective, analgesic, and antipyretic drug. Gardenoside was shown to be effective toward HCl/et...
Status:
US Previously Marketed
First approved in 1960

Class (Stereo):
CHEMICAL (ACHIRAL)



Oxethazaine is a potent local anesthetic. It is administered orally (usually in combination with an antacid) for the relief of pain associated with peptic ulcer disease or esophagitis. Its effectiveness at the acidity of the gastric environment is du...
Status:
Possibly Marketed Outside US
First approved in 2023

Class (Stereo):
CHEMICAL (ACHIRAL)


Sodium gualenate (Azunol ST Tablets) is a water-soluble derivative of azulene, a natural product which is an antiinflammatory component of chamomile of the family of Asteraceae. Sodium gualenate was originally studied as an antiulcer agent, is primar...
Status:
Possibly Marketed Outside US
First approved in 2018

Class (Stereo):
CHEMICAL (ACHIRAL)



Guaiazulene is a blue compound. It is a derivative of azulene, guaiazulene is a bicyclic sesquiterpene that is a constituent of some essential oils, mainly oil of guaiac and chamomile oil. Guaiazulene is an U.S. FDA-approved cosmetic color additive. ...
Status:
Possibly Marketed Outside US
First approved in 2010

Class (Stereo):
CHEMICAL (ACHIRAL)



Tetraprenylacetone (Geranylgeranylacetone) is an anti-peptic ulcer drug developed and approved in Japan in 1984. Tetraprenylacetone is shown to suppress H. pylori induced tissue and cell injury and inflammatory reaction, so it is expected to show ben...
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)



Plaunotol [(2E, 6Z, 10E)-7-hydroxymethyl-3,11,15-trimethyl-2,6,10, 14-hexadecatetraen-1-ol)] is an acyclic diterpene alcohol originally isolated from the plant Croton sublyratus, which is native to southeast Asia. Plaunotol has been used to treat gas...