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Details

Stereochemistry ACHIRAL
Molecular Formula S
Molecular Weight 32.065
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -2

SHOW SMILES / InChI
Structure of SULFIDE ION

SMILES

[S--]

InChI

InChIKey=UCKMPCXJQFINFW-UHFFFAOYSA-N
InChI=1S/S/q-2

HIDE SMILES / InChI

Description

A sulfide ion is composed of a lone sulfur atom. Its charge is negative two, giving sulfides this formula: S^2-. Sulfide is a strong base, so solutions of sulfide in water are basic, due to hydrolysis. One well-known ionic compound with a sulfide ion is H_2S. The infamous rotten-egg smell often associated with sulfur originates from this compound. Sodium sulfide nonahydrate is used in the formation of surface functionalized cadmium sulfide quantum dots.

CNS Activity

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
1.7 µM [Ki]
9.0 µM [IC50]
10.0 µM [IC50]
4.1 µM [IC50]
5.0 nM [IC50]
0.7 µM [IC50]
0.42 µM [IC50]
7.2 null [pKi]
8.2 null [pKi]
7.4 null [pKi]
8.2 null [pKi]
8.2 null [pKi]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
DR. SCHOLLS INGROWN TOENAIL PAIN RELIEVER
Primary
Unknown
Primary
Unknown
Primary
Unknown
Primary
Unknown
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
10-40 uM S07662 attenuates the phenytoin- and 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime (CITCO)-induced expression of CYP2B6 mRNA in human primary hepatocytes.