U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 101 - 110 of 186 results

Status:
Investigational
Source:
INN:azabuperone
Source URL:

Class (Stereo):
CHEMICAL (RACEMIC)

Azabyperone was developed as tranquilizer and neuroleptic and has never been marketed.
Status:
Investigational
Source:
INN:dimabefylline
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Dimabefylline an antiasthmatic, bronchospasmolytic drug. Also, it might be used as coronary dilator, cardiac stimulant.
Status:
Investigational
Source:
INN:erizepine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Erizepine is a compound with neuroleptic activity. Erizepine is considered to bind dopamine receptors.
Status:
Investigational
Source:
INN:trocimine [INN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

Trocimine (N-3,4,5-trimethoxybenzoylheptamethylenimine) is heptamethylenimine derivative with antidepressant activity.
Status:
Investigational
Source:
INN:lodiperone
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Lodiperon exhibited neuroleptic activity with very low liability to the extrapyramidal side effects. Its activity was greater than that of butropipazone and fluanisone, while of the same order of that of chlorpromazine; however, lodiperon showed a longer lasting activity and minor ability to produce catalepsy as compared with the reference drugs.
Status:
Investigational
Source:
INN:elfazepam
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Elfazepam is a benzodiazepine and a feed intake stimulant. Administration of elfazepam can induce animals to eat large meals. While rumen fermentation per se is not influenced by elfazepam, ruminal and abomasal motility and secretory functions are reduced.
Fluprazine (previously known as DU27716), a psychoactive drug was studied as a behaviorally selective, anti-aggressive agent. Experiments on rodents have shown that fluprazine didn’t appreciably affect defensive attack or other defensive behaviors even though it strongly inhibited offensive attack. This agent is used to test both differences and similarities in neurochemical substrates and adaptive significance of different forms of intraspecific aggression.
Status:
Investigational
Source:
INN:amoxecaine
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

AMOXECAINE is an local anaesthetic.
Status:
Investigational
Source:
INN:thiohexamide
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Thiohexamide is a first-generation, cyclohexyl-containing sulfonylurea with antihyperglycemic activity. The hypoglycemogenic activity of thiohexamide was detected in fasting, stable diabetic subjects.
Status:
Investigational
Source:
USAN:ICOTIDINE [USAN]
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Icotidine (also known as SKF 93319) was developed as histamine H1- and H2-receptor antagonist and possessed antinociception properties. Due to its antagonist activity, was suggested that compound could have therapeutic in some inflammatory skin diseases such as the urticarias and mastocytosis.

Showing 101 - 110 of 186 results