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Details

Stereochemistry ACHIRAL
Molecular Formula C14H20N2O3S2
Molecular Weight 328.45
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THIOHEXAMIDE

SMILES

CSC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2

InChI

InChIKey=NTCZDZHUBMLJQS-UHFFFAOYSA-N
InChI=1S/C14H20N2O3S2/c1-20-12-7-9-13(10-8-12)21(18,19)16-14(17)15-11-5-3-2-4-6-11/h7-11H,2-6H2,1H3,(H2,15,16,17)

HIDE SMILES / InChI

Molecular Formula C14H20N2O3S2
Molecular Weight 328.45
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Thiohexamide is a first-generation, cyclohexyl-containing sulfonylurea with antihyperglycemic activity. The hypoglycemogenic activity of thiohexamide was detected in fasting, stable diabetic subjects.

Approval Year

PubMed

PubMed

TitleDatePubMed
Comparative pharmacology of the sulfonylureas.
1962 Apr
Patents

Patents

Sample Use Guides

250, 500, and 1000 mg
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:31:36 GMT 2023
Edited
by admin
on Fri Dec 15 15:31:36 GMT 2023
Record UNII
6M8CV4TKXL
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
THIOHEXAMIDE
INN  
INN  
Official Name English
thiohexamide [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C97936
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
Code System Code Type Description
CAS
3692-44-2
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
PUBCHEM
3083819
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
INN
1133
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
EVMPD
SUB10979MIG
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
EPA CompTox
DTXSID60190411
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
FDA UNII
6M8CV4TKXL
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
SMS_ID
100000082126
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
ChEMBL
CHEMBL2107250
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
NCI_THESAURUS
C72861
Created by admin on Fri Dec 15 15:31:36 GMT 2023 , Edited by admin on Fri Dec 15 15:31:36 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY