THIOHEXAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H20N2O3S2
Molecular Weight	328.45
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CSC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2

InChI

InChIKey=NTCZDZHUBMLJQS-UHFFFAOYSA-N

InChI=1S/C14H20N2O3S2/c1-20-12-7-9-13(10-8-12)21(18,19)16-14(17)15-11-5-3-2-4-6-11/h7-11H,2-6H2,1H3,(H2,15,16,17)

HIDE SMILES / InChI

Molecular Formula	C14H20N2O3S2
Molecular Weight	328.45
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14489728

Thiohexamide is a first-generation, cyclohexyl-containing sulfonylurea with antihyperglycemic activity. The hypoglycemogenic activity of thiohexamide was detected in fasting, stable diabetic subjects.

Originator

Approval Year

PubMed

Title	Date	PubMed
Comparative pharmacology of the sulfonylureas.	1962-04	14489728

Patents

Sample Use Guides

In Vivo Use Guide

250, 500, and 1000 mg

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:00:03 GMT 2025` Edited by `admin` on `Mon Mar 31 18:00:03 GMT 2025`
Record UNII	6M8CV4TKXL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

thiohexamide [INN]

Preferred Name

English

THIOHEXAMIDE

Official Name

English

Classification Tree Code System Code

NCI_THESAURUS

C97936