| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H25N5O2 |
| Molecular Weight | 379.4555 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=CN=C1CCCCNC2=NC(=O)C(CC3=CC=C(C)N=C3)=CN2
InChI
InChIKey=GJCSPRIRQYWXRW-UHFFFAOYSA-N
InChI=1S/C21H25N5O2/c1-15-8-9-16(13-24-15)12-17-14-25-21(26-20(17)27)23-10-4-3-6-18-19(28-2)7-5-11-22-18/h5,7-9,11,13-14H,3-4,6,10,12H2,1-2H3,(H2,23,25,26,27)
Icotidine (also known as SKF 93319) was developed as histamine H1- and H2-receptor antagonist and possessed antinociception properties. Due to its antagonist activity, was suggested that compound could have therapeutic in some inflammatory skin diseases such as the urticarias and mastocytosis.
Approval Year
PubMed
ACTIVE MOIETY
