TROCIMINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H25NO4
Molecular Weight	307.3847
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TROCIMINE

Structure Search

SMILES

COC1=CC(=CC(OC)=C1OC)C(=O)N2CCCCCCC2

InChI

InChIKey=WZSDNEJJUSYNSG-UHFFFAOYSA-N

InChI=1S/C17H25NO4/c1-20-14-11-13(12-15(21-2)16(14)22-3)17(19)18-9-7-5-4-6-8-10-18/h11-12H,4-10H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C17H25NO4
Molecular Weight	307.3847
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.sciencedirect.com/science/article/pii/S0022354915362535?via%3Dihub
Curator's Comment: The description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14209499 | https://www.ncbi.nlm.nih.gov/pubmed/5395660

Trocimine (N-3,4,5-trimethoxybenzoylheptamethylenimine) is heptamethylenimine derivative with antidepressant activity.

Originator

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Depression 235 Sources: http://www.sciencedirect.com/science/article/pii/S0022354915362535?via%3Dihub	Primary		Basic research	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
Pharmacological studies with N-3,4,5-trimethoxybenzoyl-heptamethylene imine (N-1157), a new antidepressant agent.	1969 Nov	5395660

Patents

Patents

Sample Use Guides

In Vivo Use Guide

In mice the LD50 was 170mg/kg i.p. 200mg/kg s.c.

Route of Administration: Intraperitoneal

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:35:50 GMT 2023` Edited by `admin` on `Fri Dec 15 15:35:50 GMT 2023`
Record UNII	8EE22OKO88
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TROCIMINE

Official Name

English

OCTAHYDRO-1-(3,4,5-TRIMETHOXYBENZOYL)AZOCINE

Systematic Name

English

trocimine [INN]

Common Name

English

NSC-233082

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C265

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

Code System Code Type Description

SMS_ID

100000076954

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

PRIMARY

EVMPD

SUB11329MIG

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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PUBCHEM

26650

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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EPA CompTox

DTXSID1046475

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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CAS

14368-24-2

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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NSC

233082

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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ChEMBL

CHEMBL1974057

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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NCI_THESAURUS

C152755

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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INN

3644

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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FDA UNII

8EE22OKO88

Created by admin on Fri Dec 15 15:35:50 GMT 2023 , Edited by admin on Fri Dec 15 15:35:50 GMT 2023

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Related Record Type Details


					8EE22OKO88

TROCIMINE

ACTIVE MOIETY