ELFAZEPAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H18ClFN2O3S
Molecular Weight	408.874
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCS(=O)(=O)CCN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C3=C(F)C=CC=C3

InChI

InChIKey=BSPSXMXQKZZNFP-UHFFFAOYSA-N

InChI=1S/C19H18ClFN2O3S/c1-2-27(25,26)10-9-23-17-8-7-13(20)11-15(17)19(22-12-18(23)24)14-5-3-4-6-16(14)21/h3-8,11H,2,9-10,12H2,1H3

HIDE SMILES / InChI

Molecular Formula	C19H18ClFN2O3S
Molecular Weight	408.874
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/396294

Elfazepam is a benzodiazepine and a feed intake stimulant. Administration of elfazepam can induce animals to eat large meals. While rumen fermentation per se is not influenced by elfazepam, ruminal and abomasal motility and secretory functions are reduced.

Approval Year

PubMed

Title	Date	PubMed
Abomasal function following injections of elfazepam and 9-aza-cannabinol.	1979 Jan	35793
Feeding and depression of abomasal secretion in sheep elicited by elfazepam and 9-aza-cannabinol.	1979 Jul	493298
A review of the behavioral and physiological responses to elfazepam, a chemical feed intake stimulant.	1979 Nov	396294
Endotoxin-elicited fever and anorexia and elfazepam-stimulated feeding in sheep.	1981 Aug	7029576

Patents

Sample Use Guides

In Vivo Use Guide

Elfazepam added to the feed of cattle (.5 to 2.0 ppm) and of sheep (4 ppm) improved feed efficiency

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:35:18 UTC 2023` Edited by `admin` on `Fri Dec 15 15:35:18 UTC 2023`
Record UNII	RM53R5R2BL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ELFAZEPAM

Official Name

English

elfazepam [INN]

Common Name

English

2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1-(2-(ETHYLSULFONYL)ETHYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-

Systematic Name

English

NSC-297938

Code

English

ELFAZEPAM [USAN]

Common Name

English

SK&F-72517

Code

English

7-CHLORO-1-(2-(ETHYLSULFONYL)ETHYL)-5-(O-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE

Common Name

English

SK&F 72517

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C1012