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Status:
First approved in 1959
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Chlorindanol is an antiseptic agent which is rapidly leathal to vegetative bacteria (Trichophyton sp., C. albicans, E. histolytica cysts and trophozoites, T. vaginalis) and seprmatozoa in vitro. It is one of two active ingredients in a spermicidal contraceptive aerosol cream (Lanettes); with the other being laureth-9.
Status:
US Previously Marketed
Source:
ROLICTON by SEARLE
(1961)
Source URL:
First approved in 1956
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
AMISOMETRADINE, a pyrimidinedione-based diuretic, is an isomer of aminometradine with less toxicity and a reasonable diuretic potency.
Status:
US Previously Marketed
Source:
CAMOFORM by PD
(1961)
Source URL:
First approved in 1956
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
BIALAMICOL is a hydroxybiphenyl antiprotozoal used for the treatment of acute and chronic amoebiasis.
Status:
US Previously Marketed
First approved in 1956
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
ALKOFANONE is a dihydrochalcone used as an antidiarrheal agent.
Status:
First approved in 1956
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
CHLORISONDAMINE is a nicotinic acetylcholine receptor antagonist used as a ganglionic blocking agent in animal research. It was used precedently in the prolonged treatment of hypertension.
Status:
US Previously Marketed
First approved in 1956
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Benzoylpas (more known as calcium benzoyl-PAS) is a benzoic acid-modified form of para-aminosalicylate, used to treat pulmonary tuberculosis.
Status:
First approved in 1956
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Aminitrozole (Tritheon), also known as nithiamide, for some years has been successfully used in medicated feeds in the prevention of enterohepatitis (blackhead disease) in turkeys. Besides, this drug was studied in human for the treatment of trichomoniasis. Sixteen patients with vaginal trichomoniasis have been treated with Tritheon tablets. As a result, in all the thirteen patients followed, T. vaginitis was recovered after therapy. No untoward side-effects were noted, but the clinical results were uniformly bad.
Status:
First approved in 1955
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Diphenadione is a vitamin K antagonist that exhibits anticoagulant effects and is used as a rodenticide against rats, mice, voles, ground squirrels and others. When orally ingested it is toxic to mammals causing irregular heartbeat and major maladies associated with its impact on blood clotting. It is also used in South America to control vampire bat populations.
Status:
US Previously Marketed
First approved in 1955
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Azacyclonol (aka gamma-pipradrol) is an ataractive agent; a compound which diminished hallucinations in psychotic individuals. It is sometimes referred to as a tranquilizer or antipsychotic, though it does not actually possess these properties. It was used in Europe during the 1950's for treatment of schizophrenia; likely to reduce the psychedelic effects of LSD and mescaline. However, it had mixed clinical effectiveness and did not gain widespread adoption and was eventually discontinued. Azacyclonol was sold under several trade names: Ataractan, Calmeran, Frenoton, Frenquel and Psychosan.
Status:
First approved in 1955
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
GLAUCARUBIN is a quassinoid isolated from Simaruba glauca, a tropical shrub. It is used as an antiamebic agent.