Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H9ClO |
| Molecular Weight | 168.62 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=C(Cl)C2=C1CCC2
InChI
InChIKey=ATAJVFBUUIBIEO-UHFFFAOYSA-N
InChI=1S/C9H9ClO/c10-8-4-5-9(11)7-3-1-2-6(7)8/h4-5,11H,1-3H2
Chlorindanol is an antiseptic agent which is rapidly leathal to vegetative bacteria (Trichophyton sp., C. albicans, E. histolytica cysts and trophozoites, T. vaginalis) and seprmatozoa in vitro. It is one of two active ingredients in a spermicidal contraceptive aerosol cream (Lanettes); with the other being laureth-9.
Approval Year
Sample Use Guides
A spermicidal aerosol cream marketed under the name Lanettes contains 0.1 % w/w Chlorindanol as one of two active ingredients. Instructions for use describe liberal application inside the vagina and to the penile surface.
Route of Administration:
Topical
The antifungal properties of chlorindanol were assesed against yeast fungal species including Candida albicans, C. tropicalis, C. parapsilosis, C. pseudotropicalis, C. stellatoidea, C. guilliermondii, C. krusei and Torulopsis glabrata. Chlorindanol was prepared in 5% propylene glycol. Chlorindanol was found to be fungicidal at a concentration of 60 - 80 microg/mL/24 hours and fungistatic at a concentration of 20 - 40 microg/mL/24 hours. Similar activities were obseved for cultures in human seerum.
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NCI_THESAURUS |
C28394
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EPA PESTICIDE CODE |
600003
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CHEMBL1449249
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145-94-8
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158565
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DTXSID5041774
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2157
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m110
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C77037
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100000084007
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7902N03BH0
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SUB06759MIG
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8961
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1561
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ACTIVE MOIETY
