ALKOFANONE

US Previously Marketed

First approved in 1956

NC1=CC=C(C=C1)S(=O)(=O)C(CC(=O)C2=CC=CC=C2)C3=CC=CC=C3

InChIKey=VWEMSUCCUQSLME-UHFFFAOYSA-N

InChI=1S/C21H19NO3S/c22-18-11-13-19(14-12-18)26(24,25)21(17-9-5-2-6-10-17)15-20(23)16-7-3-1-4-8-16/h1-14,21H,15,22H2

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

ALKOFANONE is a dihydrochalcone used as an antidiarrheal agent.

Conditions

Condition	Modality	Targets	Highest Phase	Product
Diarrhea 35 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14495383	Primary		Not Provided 504	Unknown Approved Use Unknown

Sourcing

Vendor/Aggregator	ID	URL
ABI Chem	AC1L2N8M
NovoSeek	24145
ZINC	ZINC000002036959	http://zinc15.docking.org/substances/ZINC000002036959
ZINC	ZINC000002036960	http://zinc15.docking.org/substances/ZINC000002036960
eMolecules	260194017

PubMed

Title	Date	PubMed
Alkofanone in the treatment of simple diarrhea in children.	1961 Oct	14495383

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:41:51 GMT 2023` Edited by `admin` on `Fri Dec 15 18:41:51 GMT 2023`
Record UNII	96JNQ0UCWD
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ALKOFANONE

Common Name

English

(±)-3-((4-AMINOPHENYL)SULFONYL)-1,3-DIPHENYL-1-PROPANONE

Systematic Name

English

ALKOFANONE [MI]

Common Name

English

3-((4-AMINOPHENYL)SULFONYL)-1,3-DIPHENYL-1-PROPANONE

Systematic Name

English

ALFONE

Common Name

English

Code System Code Type Description

MERCK INDEX

m548