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Showing 1 - 10 of 75 results

Status:
US Approved Rx (2010)
First approved in 2004

Class (Stereo):
CHEMICAL (ACHIRAL)



Trospium is an antispasmodic, antimuscarinic agent indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency. Receptor assays showed that trospium has negligible affinity for nicotini...
Status:
US Approved Rx (2008)
First approved in 1979

Class (Stereo):
CHEMICAL (ACHIRAL)



Metoclopramide is a dopamine D2 antagonist that is used as an antiemetic. Metoclopramide inhibits gastric smooth muscle relaxation produced by dopamine, therefore increasing cholinergic response of the gastrointestinal smooth muscle. It accelerates i...
Status:
US Approved Rx (2009)
First approved in 1961

Class (Stereo):
CHEMICAL (RACEMIC)



Glycopyrrolate is a synthetic anticholinergic agent with a quaternary ammonium structure. Glycopyrrolate is a muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with s...
Status:
US Approved Rx (1966)
First approved in 1956

Class (Stereo):
CHEMICAL (ACHIRAL)



LIBRAX® combines in a single capsule formulation the antianxiety action of chlordiazepoxide hydrochloride and the anticholinergic/spasmolytic effects of clidinium bromide. Chlordiazepoxide hydrochloride is a versatile, therapeutic agent of proven val...
Status:
US Approved Rx (2011)
First approved in 1953

Class (Stereo):
CHEMICAL (ABSOLUTE)



Methscopolamine bromide is an anticholinergic agent used along with other medications to treat peptic ulcers by reducing stomach acid secretion. Methscopolamine is also commonly used as a drying agent, to dry up post-nasal drip, in cold, irritable bo...
Status:
US Approved Rx (1983)
First approved in 1943

Class (Stereo):
CHEMICAL (EPIMERIC)


Conditions:

Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. It is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous sy...
Status:
US Approved Rx (2021)
First marketed in 1931

Class (Stereo):
CHEMICAL (ACHIRAL)



Neostigmine is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier. By inhi...
Status:
US Approved Rx (2024)
First marketed in 1921

Class (Stereo):
CHEMICAL (RACEMIC)



Atropine inhibits the muscarinic actions of acetylcholine on structures innervated by postganglionic cholinergic nerves, and on smooth muscles which respond to endogenous acetylcholine but are not so innervated. As with other antimuscarinic agents, t...
Status:
Investigational

Class (Stereo):
CHEMICAL (RACEMIC)

Benzetimide, a muscarinic acetylcholine receptor antagonist that was investigated as an antiparkinson-agent and was studied in the treatment of diarrheas of cattle and calves. Benzetimide is an enantiomer of dexetimide that has been used to treat neu...
Status:
US Previously Marketed
First approved in 1958

Class (Stereo):
CHEMICAL (ACHIRAL)

Ambutonium is anticholinergic agent. It is a muscarinic antagonist. Ambutonium was used for the treatment of ulcerous disease and gastrointestinal disease in general.