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Showing 1 - 10 of 55 results

Status:
US Approved Rx (2014)
First approved in 2014

Class (Stereo):
CHEMICAL (ABSOLUTE)



Suvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R. It has been approved for the treatment of insomnia. The mechanism by which suvorexant exerts its therapeutic effect in insomnia is presumed to be through antagonism of orexi...
Status:
US Approved Rx (2018)
First approved in 2011

Class (Stereo):
CHEMICAL (ACHIRAL)



Clobazam belongs to the 1,5-benzodiazepine class of drugs with antiepileptic properties. It has been used to treat anxiety and epilepsy since 1970s. In the US clobazam was approved for marketing in October of 2011 for the adjunctive treatment of seiz...
Status:
US Approved Rx (2008)
First approved in 1999

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Zaleplon is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class and is indicated for the short-term treatment of insomnia. While Zaleplon is a hypnotic agent with a chemical structure unrelated to benzodiazepines, barbiturates, or other dr...
Status:
US Approved Rx (2016)
First approved in 1992

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Zolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. Zolpidem can be one of useful alternative pharmacological treatments for blepharospasm. Zol...
Status:
US Approved Rx (1997)
First approved in 1990

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Estazolam, a triazolobenzodiazepine derivative, is an oral hypnotic agent with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam. Benzodiazepines bind nonspecifical...
Status:
US Approved Rx (2018)
First approved in 1989

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Propofol (2,6-diisopropylphenol) is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combinati...
Status:
US Approved Rx (1985)
First approved in 1985

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Quazepam is indicated for the treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings. Quazepam interact preferentially with the benzodiazepine-1 (BZ1) receptors. Most common...
Status:
US Approved Rx (2000)
First approved in 1985

Class (Stereo):
CHEMICAL (ACHIRAL)



Midazolam, previously marketed under the trade name Versed, is a medication used for anesthesia, procedural sedation, trouble sleeping, and severe agitation. Midazolam is a short-acting benzodiazepine central nervous system (CNS) depressant. Pharmaco...
Status:
US Approved Rx (2020)
First approved in 1982

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Triazolam is a short-acting benzodiazepine used as a hypnotic agent in the treatment of insomnia. Some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher ...
Status:
US Approved Rx (2023)
First approved in 1981

Class (Stereo):
CHEMICAL (RACEMIC)


Conditions:

Temazepam is a benzodiazepine used as a hypnotic agent in the management of insomnia. Temazepam produces CNS depression at limbic, thalamic, and hypothalamic levels of the CNS. Temazepam increases the affinity of the neurotransmitter gamma-aminobutyr...