Search results for "ATC|CARDIOVASCULAR SYSTEM|ANTIHYPERTENSIVES|ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON" in comments (approximate match)
Showing 1 - 9 of 9 results
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Minoxidil is an orally effective direct acting peripheral vasodilator that reduces elevated systolic and diastolic blood pressure by decreasing peripheral vascular resistance. Minoxidil is also used topically to treat androgenetic alopecia. Microcirc...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Diazoxide is a drug which was approved by FDA for the treatment of secondary hyperinsulinemia. The drug exerts its action by binding to SUR1 subunit of ATP-sensitive potassium channel that leads to the channel opening.
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Hydralazine is a direct-acting vasodilator that is used as an antihypertensive agent. Hydralazine works by relaxing blood vessels (arterioles more than venules) and increasing the supply of blood and oxygen to the heart while reducing its workload. I...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Pinacidil is a clinically effective vasodilator used for the treatment of hypertension.
Class (Stereo):
CHEMICAL (RACEMIC)
Conditions:
Cadralazine is an antihypertensive of the hydrazinophthalazine chemical class. In hypertensive patients the optimal effect, based on the antihypertensive efficacy to tolerability ratio, is seen after a 15 mg dose when the drug is administered as mono...
Class (Stereo):
CHEMICAL (ACHIRAL)
Conditions:
Dihydralazine is a compound with antihypertensive properties and is in clinical trials, where is studied its effect on kidney function and hormones in healthy individuals.
Endralazine (6-benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido-(4,3-c)-pyridazine mesylate) is a peripheral vasodilator drug, which acts by direct relaxation of the smooth muscle fibres of the peripheral arterial vessels. Endralazine has been used as an...
Class (Stereo):
CHEMICAL (OCTAHEDRAL 22)
Targets:
Conditions:
Pentaerythritol tetranitrate is an organic nitrate that has been used for the treatment of angina pectoris. Upon administration, the drug undergoes exstensive metabolism to NO which causes vasodilation and the relaxation of smooth muscle cells. The c...
Class (Stereo):
CHEMICAL (RACEMIC)
Targets:
Conditions:
Pinacidil is a clinically effective vasodilator used for the treatment of hypertension.