ENDRALAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H15N5O
Molecular Weight	269.3018
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of ENDRALAZINE

Structure Search

SMILES

N\N=C1/NN=C2CCN(CC2=C1)C(=O)C3=CC=CC=C3

InChI

InChIKey=ALAXZYHFVBSJKZ-UHFFFAOYSA-N

InChI=1S/C14H15N5O/c15-16-13-8-11-9-19(7-6-12(11)17-18-13)14(20)10-4-2-1-3-5-10/h1-5,8H,6-7,9,15H2,(H,16,18)

HIDE SMILES / InChI

Molecular Formula	C14H15N5O
Molecular Weight	269.3018
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6861845 | https://www.ncbi.nlm.nih.gov/pubmed/3758143

Endralazine (6-benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido-(4,3-c)-pyridazine mesylate) is a peripheral vasodilator drug, which acts by direct relaxation of the smooth muscle fibres of the peripheral arterial vessels. Endralazine has been used as an antihypertensive agent.

Approval Year

PubMed

PubMed

Title	Date	PubMed

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:34:24 UTC 2023` Edited by `admin` on `Fri Dec 15 15:34:24 UTC 2023`
Record UNII	L44741F05P
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ENDRALAZINE

Official Name

English

endralazine [INN]

Common Name

English

Endralazine [WHO-DD]

Common Name

English

6-BENZOYL-5,6,7,8-TETRAHYDROPYRIDO(4,3-C)PYRIDAZIN-3(2H)-ONE HYDRAZONE

Systematic Name

English

ENDRALAZINE [MI]

Common Name

English

PYRIDO(4,3-C)PYRIDAZIN-3(2H)-ONE, 6-BENZOYL-5,6,7,8-TETRAHYDRO-, HYDRAZONE

Systematic Name

English

Classification Tree Code System Code

WHO-VATC

QC02DB03

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

NCI_THESAURUS

C29707

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

WHO-ATC

C02DB03

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

Code System Code Type Description

FDA UNII

L44741F05P

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

PRIMARY

SMS_ID

100000080227

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

PRIMARY

MERCK INDEX

m4902

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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Merck Index

ChEMBL

CHEMBL254193

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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PUBCHEM

47608

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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CAS

39715-02-1

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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EPA CompTox

DTXSID40192791

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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DRUG CENTRAL

1008

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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WIKIPEDIA

ENDRALAZINE

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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DRUG BANK

DB13435

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

PRIMARY

EVMPD

SUB06525MIG

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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INN

4288

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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NCI_THESAURUS

C77151

Created by admin on Fri Dec 15 15:34:24 UTC 2023 , Edited by admin on Fri Dec 15 15:34:24 UTC 2023

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Related Record Type Details


					333M5986I5

ENDRALAZINE MESYLATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					L44741F05P

ACTIVE MOIETY