ENDRALAZINE MESYLATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H15N5O.CH4O3S
Molecular Weight	365.407
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CS(O)(=O)=O.N\N=C1/NN=C2CCN(CC2=C1)C(=O)C3=CC=CC=C3

InChI

InChIKey=HMVROCAATOPFHB-UHFFFAOYSA-N

InChI=1S/C14H15N5O.CH4O3S/c15-16-13-8-11-9-19(7-6-12(11)17-18-13)14(20)10-4-2-1-3-5-10;1-5(2,3)4/h1-5,8H,6-7,9,15H2,(H,16,18);1H3,(H,2,3,4)

HIDE SMILES / InChI

Molecular Formula	CH4O3S
Molecular Weight	96.106
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H15N5O
Molecular Weight	269.3018
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6861845 | https://www.ncbi.nlm.nih.gov/pubmed/3758143

Endralazine (6-benzoyl-3-hydrazino-5,6,7,8-tetrahydropyrido-(4,3-c)-pyridazine mesylate) is a peripheral vasodilator drug, which acts by direct relaxation of the smooth muscle fibres of the peripheral arterial vessels. Endralazine has been used as an antihypertensive agent.

Approval Year

PubMed

Title	Date	PubMed

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:03 GMT 2023` Edited by `admin` on `Fri Dec 15 15:16:03 GMT 2023`
Record UNII	333M5986I5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ENDRALAZINE MESYLATE

Official Name

English

Endralazine mesilate [WHO-DD]

Common Name

English

ENDRALAZINE MESYLATE [USAN]

Common Name

English

ENDRALAZINE METHANESULFONATE [MI]

Common Name

English

NSC-310289

Code

English

22-708

Code

English

ENDRALAZINE MESILATE [MART.]

Common Name

English

ENDRALAZINE MESILATE

Common Name

English

ENDRALAZINE METHANESULFONATE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707