U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 8501 - 8510 of 8601 results

Status:
US Previously Marketed
Source:
Ammonium Hypophosphite N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Ammonium Hypophosphite N.F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Hypophosphite is a strong reducing agent, that has been used in the 1850s as a remedy for pulmonary tuberculosis. Hypophosphites were used extensively in pharmaceutical preparations, elixirs, and tonics. Hypophosphite does not appear to have adverse toxicological effects, and the sodium, calcium, and potassium salts are considered GRAS. Hypophosphite use in foods may not be limited to one function. Hypophosphites have been used in foods as antioxidants, stabilizers, meat pickling accelerator, and vegetable protein flow inducer.
Status:
US Previously Marketed
Source:
Hydrochloric Acid U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Hydrochloric Acid U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


HYDROCHLORIC ACID is formed by dissolving hydrogen chloride gas in water. It is a strong corrosive acid that is commonly used as a laboratory reagent. Also, it constitutes the majority of gastric acid, the human digestive fluid. Skin contact with HYDROCHLORIC ACID can cause redness, pain, and severe skin burns. It may cause severe burns to the eye and permanent eye damage.
Status:
US Previously Marketed
Source:
Exsiccated Sodium Sulphite U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Exsiccated Sodium Sulphite U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Sulfites are compounds that contain the sulfite ion. The sulfite ion is the conjugate base of bisulfite. Although its acid is elusive, its salts are widely used. Sulfite is used in the photography industry to protect developing solutions from oxidation, in the pulp and paper industry, in water treatment as an oxygen scavenger agent, as a desulfurizing and dechlorinating agent in the leather industry and as a bleaching agent in textile industry. Sodium sulfite is a component in many pharmaceuticals, which is effective to maintain the potency and stability of drugs. It is added to a number of drug preparations as an antioxidant and antimicrobial agent. Sulfite is used as a food preservative. Topical, oral or parenteral exposure to sulphites has been reported to induce a range of adverse clinical effects in sensitive individuals, ranging from dermatitis, urticaria, flushing, hypotension, abdominal pain and diarrhoea to life-threatening anaphylactic and asthmatic reactions. Exposure to the sulphites arises mainly from the consumption of foods and drinks that contain these additives; however, exposure may also occur through the use of pharmaceutical products, as well as in occupational settings. Sulfite is accepted for use as a food additive in Europe. Sodium sulfite is generally recognized as safe by FDA. It is included in FDA Inactive Ingredients Database (epidural, IM, IV, and SC injections; inhalation solution; ophthalmic solutions; oral syrups and suspensions; otic solutions; topical creams and emulsions). Included in nonparenteral medicines licensed in the UK.
Status:
US Previously Marketed
Source:
Sodium Arsenate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sodium Arsenate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ammonium dihydrogen arsenate is an inorganic compound that has been considered a potential electro-optic material and has been explored by a number of investigators for modulation purposes. Ammonium arsenate is a cancerogenic substance.
Status:
US Previously Marketed
Source:
Sodium Arsenate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Sodium Arsenate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Ammonium dihydrogen arsenate is an inorganic compound that has been considered a potential electro-optic material and has been explored by a number of investigators for modulation purposes. Ammonium arsenate is a cancerogenic substance.
Aconitic Acid found in leaves and tubers of Aconitum napellus L., Ranunculaceae, in various species of Achillea (Compositae) and Equisetum (Equisetaceae), in beet root, and in sugar cane. It is indicated for the temporary relief of symptoms of chronic illness including fatigue, effects of toxin buildup, slowed metabolism, weakened constitution. The limited data on trans-aconitic acid indicate it to be less toxic than citric acid. Trans-aconitate salts appear to be excreted readily by the kidneys. There is no direct evidence that trans-aconitic acid is utilized as is the cis-aconitic acid isomer in mammalian metabolism although non-specific oxidation probably occurs.
Status:
Possibly Marketed Outside US

Class (Stereo):
CHEMICAL (ACHIRAL)


Conditions:

Acid green 50 (Lissamine Green B) is a synthetically produced organic acid dye with two aminophenyl groups. Acid green 50 is extensively used as a food dye and has a medical application as a staining agent. Due to its low toxicity and ability to stain dead and damaged cells the dye (in form of lissamine green strips) was approved as a tool for diagnosis of eye diseases associated with the damage of ocular surface epithelial cells.

Showing 8501 - 8510 of 8601 results