Details
Stereochemistry | ACHIRAL |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl
InChI
InChIKey=VEXZGXHMUGYJMC-UHFFFAOYSA-N
InChI=1S/ClH/h1H
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
HYDROCHLORIC ACID is formed by dissolving hydrogen chloride gas in water. It is a strong corrosive acid that is commonly used as a laboratory reagent. Also, it constitutes the majority of gastric acid, the human digestive fluid. Skin contact with HYDROCHLORIC ACID can cause redness, pain, and severe skin burns. It may cause severe burns to the eye and permanent eye damage.
Approval Year
PubMed
Title | Date | PubMed |
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Catabolism of haemoglobin-haptoglobin complexes in haemolytic uraemia-like syndromes of different etiologies. | 1982 Oct |
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Gastric cytoprotection by pirenzepine in rats: evaluating method for cytoprotective activity by antisecretory agents. | 1985 Aug |
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Aging impairs afferent nerve function in rat intestine. Reduction of mesenteric hyperemia induced by intraduodenal capsaicin and acid. | 1996 Feb |
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Risk of acute bronchospasm and bronchial hyperreactivity from inhaled acid aerosol in healthy subjects: randomized, double-blind controlled trial. | 2004 Dec |
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Immunocytochemical characterization of rat brainstem neurons with vagal afferent input from the stomach challenged by acid or ammonia. | 2004 Jan |
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JTE-607, a cytokine release blocker, attenuates acid aspiration-induced lung injury in rats. | 2004 Mar 19 |
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Effects of nitric oxide synthase inhibitor on acid aspiration-induced lung injury in rats. | 2005 |
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Esophageal ATP synthase and keratinocyte growth factor gene expression changes after acid and bile-induced mucosal damage. | 2005 Apr |
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[Prophylactic effect of ambroxol on acute hydrochloric acid aspiration - induced lung injury]. | 2005 Jun |
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Independent contributions of hypothermia and acidosis to coagulopathy in swine. | 2005 May |
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Pulmonary aspiration: new therapeutic approaches in the experimental model. | 2005 Sep |
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Differential effects of intragastric acid and capsaicin on gastric emptying and afferent input to the rat spinal cord and brainstem. | 2005 Sep 14 |
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Molecular pharmacological approach to drug actions on the afferent and efferent fibres of the vagal nerve involved in gastric mucosal protection in rats. | 2006 Dec |
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Vocal cord dysfunction concurrent with a nutcracker esophagus and the role of gastroesophageal reflux disease. | 2006 Feb |
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Renal expression of the ammonia transporters, Rhbg and Rhcg, in response to chronic metabolic acidosis. | 2006 Feb |
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[Effects of different modes of artificial ventilation on lung injury in dog model of acute respiratory distress syndrome]. | 2006 Jun |
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Effects of plastoquinones from the brown alga Sargassum micracanthum and a new chromene derivative converted from the plastoquinones on acute gastric lesions in rats. | 2006 Jun |
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[Effects of lateral position and independent lung ventilation on unilateral acute lung injury in dogs]. | 2006 May |
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Expression of HSP72 in the gastric mucosa is regulated by gastric acid in rats-correlation of HSP72 expression with mucosal protection. | 2006 Oct 20 |
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Chronic metabolic acidosis alters osteoblast differentiation from human mesenchymal stem cells. | 2007 Feb |
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[Effects of recruitment maneuvers in prone position for pulmonary or extra-pulmonary acute respiratory distress syndrome on hemodynamics in dog]. | 2008 Jun |
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Hydrochloric acid aspiration increases right ventricular systolic pressure in rats. | 2009 Apr |
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The multimeric structure of polycystin-2 (TRPP2): structural-functional correlates of homo- and hetero-multimers with TRPC1. | 2009 Apr 1 |
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Permissive hypercapnia, instituted via reduction of pressure amplitude on pulmonary tissue protection during high frequency oscillatory ventilation, is not protective in a rat model of acid-induced lung injury. | 2009 Aug |
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Gastroprotective activity of alkaloid extract and 2-phenylquinoline obtained from the bark of Galipea longiflora Krause (Rutaceae). | 2009 Jul 15 |
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[The expression of substance P in airway mucosa of guinea pigs with repetitive esophageal stimulation by hydrochloric acid]. | 2009 Jun |
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Neither fibrin nor plasminogen activator inhibitor-1 deficiency protects lung function in a mouse model of acute lung injury. | 2009 Mar |
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Bladder hyperactivity and increased excitability of bladder afferent neurons associated with reduced expression of Kv1.4 alpha-subunit in rats with cystitis. | 2009 May |
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Neurally adjusted ventilatory assist decreases ventilator-induced lung injury and non-pulmonary organ dysfunction in rabbits with acute lung injury. | 2009 Nov |
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Animal study for airway inflammation triggered by gastroesophageal reflux. | 2009 Nov 20 |
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Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man. | 2009 Oct |
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Proton acts as a neurotransmitter for nicotine-induced adrenergic and calcitonin gene-related peptide-containing nerve-mediated vasodilation in the rat mesenteric artery. | 2009 Sep |
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A novel external esophageal perfusion model for reflux-associated respiratory symptoms. | 2010 |
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Influence of chronic renal failure on acid secretion in isolated gastric mucosal cells from human biopsies. | 2010 |
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Prolonged hypoxemia and acidemia in anesthetized pigs: a model for research on extracorporeal organ support in an intensive care setting. | 2010 Aug |
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Improved gas exchange and survival after KL-4 surfactant in newborn pigs with severe acute lung injury. | 2010 Aug |
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Effect of intercalated cell-specific Rh C glycoprotein deletion on basal and metabolic acidosis-stimulated renal ammonia excretion. | 2010 Aug |
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NHE4 is critical for the renal handling of ammonia in rodents. | 2010 Jun |
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Inflammatory mediators of esophagitis alter p27 Kip1 expression in esophageal epithelial cells. | 2010 Nov |
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Role of the Rhesus glycoprotein, Rh B glycoprotein, in renal ammonia excretion. | 2010 Nov |
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Expression of neutral endopeptidase activity during clinical and experimental acute lung injury. | 2010 Nov 29 |
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Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis. | 2010 Oct |
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HCl-induced inflammatory mediators in esophageal mucosa increase migration and production of H2O2 by peripheral blood leukocytes. | 2010 Sep |
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The effect of tidal volume on systemic inflammation in Acid-induced lung injury. | 2011 |
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Inhibitory effect of rosiglitazone on the acid-induced intracellular generation of hydrogen peroxide in cultured feline esophageal epithelial cells. | 2011 Feb |
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Involvement of NADPH-dependent and cAMP-PKA sensitive H+ channels in the chorda tympani nerve responses to strong acids. | 2011 May |
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JAK2-targeted anti-inflammatory effect of a resveratrol derivative 2,4-dihydroxy-N-(4-hydroxyphenyl)benzamide. | 2013 Dec 15 |
|
Chemicals inducing acute irritant contact dermatitis mobilize intracellular calcium in human keratinocytes. | 2013 Feb |
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The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: involvement of inflammatory cytokines and nitric oxide. | 2015 Jan 5 |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:43:39 GMT 2023
by
admin
on
Fri Dec 15 15:43:39 GMT 2023
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Record UNII |
QTT17582CB
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Record Status |
Validated (UNII)
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Record Version |
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-
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Classification Tree | Code System | Code | ||
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EPA PESTICIDE CODE |
45901
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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WHO-VATC |
QB05XA13
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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WHO-VATC |
QA09AB03
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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DSLD |
1445 (Number of products:1)
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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JECFA EVALUATION |
INS-507
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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WHO-ATC |
A09AB03
Created by
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WHO-ATC |
B05XA13
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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CODEX ALIMENTARIUS (GSFA) |
INS-507
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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FDA ORPHAN DRUG |
98896
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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Code System | Code | Type | Description | ||
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SUB50009
Created by
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PRIMARY | |||
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C45678
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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CONCEPT | Industrial Aid | ||
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HYDROCHLORIC ACID
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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PRIMARY | Description: A clear, colourless, fuming liquid; odour, pungent. Miscibility: Miscible with water. Category: Acidifying agent. Storage: Hydrochloric acid should be kept in a tightly closed container. Additional information: The fumes and odour disappear when the acid is diluted with 2 volumes of water. Mass density: .RHO.20 = about 1.18 g/mL. Requirement: Hydrochloric acid contains not less than 35.0% m/mand not more than the equivalent of 38.0% m/mof HCl. | ||
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4568
Created by
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PRIMARY | |||
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5486
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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PRIMARY | RxNorm | ||
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HYDROCHLORIC ACID
Created by
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PRIMARY | |||
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C76716
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PRIMARY | |||
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SUB129759
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ALTERNATIVE | |||
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313
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PRIMARY | |||
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7647-01-0
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PRIMARY | |||
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17883
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PRIMARY | |||
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m6101
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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PRIMARY | Merck Index | ||
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QTT17582CB
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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PRIMARY | |||
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CHEMBL1231821
Created by
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PRIMARY | |||
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231-595-7
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PRIMARY | |||
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m6088
Created by
admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
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PRIMARY | Merck Index | ||
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D006851
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PRIMARY | |||
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SUB12513MIG
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QTT17582CB
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PRIMARY | |||
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DB13366
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77365
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PRIMARY | |||
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100000078724
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PARENT -> IMPURITY |
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ACTIVE MOIETY |
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