U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula H2O.2AsH3O4
Molecular Weight 301.9013
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ARSENIC ACID HEMIHYDRATE

SMILES

O.O[As](O)(O)=O.O[As](O)(O)=O

InChI

InChIKey=IGZLSWCUPJLTLQ-UHFFFAOYSA-N
InChI=1S/2AsH3O4.H2O/c2*2-1(3,4)5;/h2*(H3,2,3,4,5);1H2

HIDE SMILES / InChI
Ammonium dihydrogen arsenate is an inorganic compound that has been considered a potential electro-optic material and has been explored by a number of investigators for modulation purposes. Ammonium arsenate is a cancerogenic substance.

Approval Year

PubMed

PubMed

TitleDatePubMed
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.
1994 Nov 15
Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression.
1996 Nov-Dec
Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms.
1998 Apr
Enhanced transcription factor DNA binding and gene expression induced by arsenite or arsenate in renal slices.
1999 Jul
Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans.
2003 Aug
Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
2003 Dec
Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine.
2004 Dec
Arsenic induced inhibition of delta-aminolevulinate dehydratase activity in rat blood and its response to meso 2,3-dimercaptosuccinic acid and monoisoamyl DMSA.
2004 Mar
Regulation of cytoplasmic stress granules by apoptosis-inducing factor.
2004 Sep 1
Redox regulation of RhoA.
2006 Dec 5
Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells.
2006 Jul
Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration.
2006 Nov 1
Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis.
2007 Nov
Effects of inorganic arsenic on the rat and mouse urinary bladder.
2008 Dec
High dietary fat exacerbates arsenic-induced liver fibrosis in mice.
2008 Mar
Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile.
2008 Oct 1
Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.
2009 Aug
Effects of different inorganic arsenic species in Cyprinus carpio (Cyprinidae) tissues after short-time exposure: bioaccumulation, biotransformation and biological responses.
2009 Dec
Inorganic arsenic modulates the expression of selenoproteins in mouse embryonic stem cell.
2009 Jun 1
Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.
2009 Sep 1
Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein.
2015 Mar 18
Patents
Name Type Language
ARSENIC ACID HEMIHYDRATE
Common Name English
Code System Code Type Description
PUBCHEM
202213
Created by admin on Fri Dec 15 15:24:34 GMT 2023 , Edited by admin on Fri Dec 15 15:24:34 GMT 2023
PRIMARY
FDA UNII
7U320R238A
Created by admin on Fri Dec 15 15:24:34 GMT 2023 , Edited by admin on Fri Dec 15 15:24:34 GMT 2023
PRIMARY
CAS
7774-41-6
Created by admin on Fri Dec 15 15:24:34 GMT 2023 , Edited by admin on Fri Dec 15 15:24:34 GMT 2023
PRIMARY
EPA CompTox
DTXSID80228361
Created by admin on Fri Dec 15 15:24:34 GMT 2023 , Edited by admin on Fri Dec 15 15:24:34 GMT 2023
PRIMARY