U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula H2O.2AsH3O4
Molecular Weight 301.9013
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ARSENIC ACID HEMIHYDRATE

SMILES

O.O[As](O)(O)=O.O[As](O)(O)=O

InChI

InChIKey=IGZLSWCUPJLTLQ-UHFFFAOYSA-N
InChI=1S/2AsH3O4.H2O/c2*2-1(3,4)5;/h2*(H3,2,3,4,5);1H2

HIDE SMILES / InChI

Molecular Formula AsH3O4
Molecular Weight 141.943
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ammonium dihydrogen arsenate is an inorganic compound that has been considered a potential electro-optic material and has been explored by a number of investigators for modulation purposes. Ammonium arsenate is a cancerogenic substance.

Approval Year

PubMed

PubMed

TitleDatePubMed
Role of autophagy in arsenite-induced neurotoxicity: the involvement of α-synuclein.
2015-03-18
Monomethylarsenic diglutathione transport by the human multidrug resistance protein 1 (MRP1/ABCC1).
2011-12
Fast, quantitative in situ hybridization of rare mRNAs using 14C-standards and phosphorus imaging.
2009-12-15
Effects of different inorganic arsenic species in Cyprinus carpio (Cyprinidae) tissues after short-time exposure: bioaccumulation, biotransformation and biological responses.
2009-12
Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate.
2009-10
Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.
2009-09-01
Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols.
2009-08
Inorganic arsenic modulates the expression of selenoproteins in mouse embryonic stem cell.
2009-06-01
Effects of inorganic arsenic on the rat and mouse urinary bladder.
2008-12
Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile.
2008-10-01
Arsenite-induced cytotoxicity in dorsal root ganglion explants.
2008-04-15
High dietary fat exacerbates arsenic-induced liver fibrosis in mice.
2008-03
Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis.
2007-11
Glutathione-dependent reduction of arsenate by glycogen phosphorylase responsiveness to endogenous and xenobiotic inhibitors.
2007-11
Redox regulation of RhoA.
2006-12-05
Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration.
2006-11-01
Organic anion transporting polypeptide-C mediates arsenic uptake in HEK-293 cells.
2006-07
Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children.
2005-06
Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine.
2004-12
Regulation of cytoplasmic stress granules by apoptosis-inducing factor.
2004-09-01
Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.
2004-04-13
Arsenic induced inhibition of delta-aminolevulinate dehydratase activity in rat blood and its response to meso 2,3-dimercaptosuccinic acid and monoisoamyl DMSA.
2004-03
Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
2003-12
Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes.
2003-12
Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans.
2003-08
Purine nucleoside phosphorylase as a cytosolic arsenate reductase.
2002-11
Enhanced transcription factor DNA binding and gene expression induced by arsenite or arsenate in renal slices.
1999-07
Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms.
1998-04
Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression.
1996-11-01
Screening for reproductive toxicity in Fundulus heteroclitus by genetic expression profiling.
1996
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.
1994-11-15
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:56:45 GMT 2025
Edited
by admin
on Mon Mar 31 17:56:45 GMT 2025
Record UNII
7U320R238A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ARSENIC ACID HEMIHYDRATE
Preferred Name English
Code System Code Type Description
PUBCHEM
202213
Created by admin on Mon Mar 31 17:56:45 GMT 2025 , Edited by admin on Mon Mar 31 17:56:45 GMT 2025
PRIMARY
FDA UNII
7U320R238A
Created by admin on Mon Mar 31 17:56:45 GMT 2025 , Edited by admin on Mon Mar 31 17:56:45 GMT 2025
PRIMARY
CAS
7774-41-6
Created by admin on Mon Mar 31 17:56:45 GMT 2025 , Edited by admin on Mon Mar 31 17:56:45 GMT 2025
PRIMARY
EPA CompTox
DTXSID80228361
Created by admin on Mon Mar 31 17:56:45 GMT 2025 , Edited by admin on Mon Mar 31 17:56:45 GMT 2025
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE