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Details

Stereochemistry ACHIRAL
Molecular Formula ClH
Molecular Weight 36.461
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Hydrochloric acid

SMILES

Cl

InChI

InChIKey=VEXZGXHMUGYJMC-UHFFFAOYSA-N
InChI=1S/ClH/h1H

HIDE SMILES / InChI

Description

HYDROCHLORIC ACID is formed by dissolving hydrogen chloride gas in water. It is a strong corrosive acid that is commonly used as a laboratory reagent. Also, it constitutes the majority of gastric acid, the human digestive fluid. Skin contact with HYDROCHLORIC ACID can cause redness, pain, and severe skin burns. It may cause severe burns to the eye and permanent eye damage.

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
LACTATED RINGER'S

Approved Use

Lactated Ringer’s and 5% Dextrose Injection, USP is indicated as a source of water, electrolytes and calories or as an alkalinizing agent.

Launch Date

1971
PubMed

PubMed

TitleDatePubMed
Aging impairs afferent nerve function in rat intestine. Reduction of mesenteric hyperemia induced by intraduodenal capsaicin and acid.
1996 Feb
Capsaicin-sensitive afferent sensory nerves in modulating gastric mucosal defense against noxious agents.
1999 Nov
Effect of vitamin E on aspirin-induced gastric mucosal injury in rats.
2000 Mar
Nitric oxide inhalation increases alveolar gas exchange by decreasing deadspace volume.
2001 Jun
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection.
2001 Jun
Bile-induced adenosine triphosphate depletion and mucosal damage during reflux esophagitis.
2001 May
Neutrophil proteinases in hydrochloric acid- and endotoxin-induced acute lung injury: evaluation of interstitial protease activity by in situ zymography.
2002 Feb
Expression of a 72-kDa heat shock protein, and its cytoprotective function, in gastric mucosa in cirrhotic rats.
2004 Aug
Risk of acute bronchospasm and bronchial hyperreactivity from inhaled acid aerosol in healthy subjects: randomized, double-blind controlled trial.
2004 Dec
The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice.
2004 Jul
Effects of celecoxib on acid-challenged gastric mucosa of rats: comparison with metamizol and piroxicam.
2004 Jun
Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice.
2004 Nov 1
Effects of nitric oxide synthase inhibitor on acid aspiration-induced lung injury in rats.
2005
Esophageal ATP synthase and keratinocyte growth factor gene expression changes after acid and bile-induced mucosal damage.
2005 Apr
[Prophylactic effect of ambroxol on acute hydrochloric acid aspiration - induced lung injury].
2005 Jun
Expression of HSP72 in the gastric mucosa is regulated by gastric acid in rats-correlation of HSP72 expression with mucosal protection.
2006 Oct 20
Beneficial effects of suplatast tosilate (IPD-1151T) in a rat cystitis model induced by intravesical hydrochloric acid.
2007 Oct
Muscarinic receptors involved in airway vascular leakage induced by experimental gastro-oesophageal reflux.
2008 Apr 23
Fatal myocardial infarction after hydrochloric acid ingestion in a suicide attempt.
2008 Jun
Lung injury and recovery in a murine model of unilateral acid aspiration: functional, biochemical, and morphologic characterization.
2008 Jun
Hydrochloric acid aspiration increases right ventricular systolic pressure in rats.
2009 Apr
The multimeric structure of polycystin-2 (TRPP2): structural-functional correlates of homo- and hetero-multimers with TRPC1.
2009 Apr 1
Permissive hypercapnia, instituted via reduction of pressure amplitude on pulmonary tissue protection during high frequency oscillatory ventilation, is not protective in a rat model of acid-induced lung injury.
2009 Aug
Hemodynamic effects of PEEP in a porcine model of HCl-induced mild acute lung injury.
2009 Feb
Neither fibrin nor plasminogen activator inhibitor-1 deficiency protects lung function in a mouse model of acute lung injury.
2009 Mar
Animal study for airway inflammation triggered by gastroesophageal reflux.
2009 Nov 20
Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man.
2009 Oct
Patents

Patents

03931143
17
03931151
3
03931217
10
03931239
39
03932426
35
03932479
112
03932524
68
03932644
2
03933802
2
03933906
2
03934024
2
03936418
3
03937704
32
03940411
9
03940421
2
03940486
2
03943154
9
03946001
3
03947417
2
03947445
3
03947582
12
03948955
2
03950380
3
03950390
2
03950393
3
03950406
119
03950423
2
03951976
2
03951980
4
03953402
2
Name Type Language
Hydrochloric acid
FCC   HSDB   II   INCI   MART.   MI   VANDF   WHO-DD   WHO-IP  
INCI  
Official Name English
BAUME HCL
Common Name English
E-507
Code English
HYDROCHLORIC ACID [MART.]
Common Name English
MURIATICUM ACIDUM [HPUS]
Common Name English
ACIDUM HYDROCHLORICUM [WHO-IP LATIN]
Common Name English
HYDROCHLORIC ACID [JAN]
Common Name English
ICON ETCH
Common Name English
HYDROCHLORIC ACID [WHO-IP]
Common Name English
HYDROCHLORIC ACID [VANDF]
Common Name English
INS-507
Code English
INS NO.507
Code English
HYDROCHLORIC ACID [FCC]
Common Name English
ANHYDROUS HYDROCHLORIC ACID
Common Name English
HYDROCHLORIC ACID [IARC]
Common Name English
HYDROGEN CHLORIDE
MI  
Systematic Name English
HYDROCHLORIC ACID [INCI]
Common Name English
MURIATIC ACID
Common Name English
HYDROCHLORIC ACID [MI]
Common Name English
HYDROGEN CHLORIDE [MI]
Common Name English
HYDROCHLORIC ACID [II]
Common Name English
HYDROCHLORIC ACID [HSDB]
Common Name English
NSC-77365
Code English
Hydrochloric acid [WHO-DD]
Common Name English
MURIATICUM ACIDUM
HPUS  
Common Name English
ENPLATE PO 236
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 45901
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
WHO-VATC QB05XA13
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
WHO-VATC QA09AB03
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
DSLD 1445 (Number of products:1)
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
JECFA EVALUATION INS-507
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
WHO-ATC A09AB03
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
WHO-ATC B05XA13
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
CODEX ALIMENTARIUS (GSFA) INS-507
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
FDA ORPHAN DRUG 98896
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
Code System Code Type Description
EVMPD
SUB50009
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
CONCEPT Industrial Aid
WHO INTERNATIONAL PHARMACOPEIA
HYDROCHLORIC ACID
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY Description: A clear, colourless, fuming liquid; odour, pungent. Miscibility: Miscible with water. Category: Acidifying agent. Storage: Hydrochloric acid should be kept in a tightly closed container. Additional information: The fumes and odour disappear when the acid is diluted with 2 volumes of water. Mass density: .RHO.20 = about 1.18 g/mL. Requirement: Hydrochloric acid contains not less than 35.0% m/mand not more than the equivalent of 38.0% m/mof HCl.
DRUG CENTRAL
4568
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
RXCUI
5486
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY RxNorm
WIKIPEDIA
HYDROCHLORIC ACID
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
NCI_THESAURUS
C76716
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
EVMPD
SUB129759
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
ALTERNATIVE
PUBCHEM
313
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
CAS
7647-01-0
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
CHEBI
17883
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
MERCK INDEX
m6101
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY Merck Index
DAILYMED
QTT17582CB
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
ChEMBL
CHEMBL1231821
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
ECHA (EC/EINECS)
231-595-7
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
MERCK INDEX
m6088
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY Merck Index
MESH
D006851
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
EVMPD
SUB12513MIG
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
FDA UNII
QTT17582CB
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
DRUG BANK
DB13366
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
NSC
77365
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
SMS_ID
100000078724
Created by admin on Fri Dec 15 15:43:39 GMT 2023 , Edited by admin on Fri Dec 15 15:43:39 GMT 2023
PRIMARY
NIH
NCATS
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