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Details

Stereochemistry ACHIRAL
Molecular Formula ClH
Molecular Weight 36.461
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Hydrochloric Acid

SMILES

Cl

InChI

InChIKey=VEXZGXHMUGYJMC-UHFFFAOYSA-N
InChI=1S/ClH/h1H

HIDE SMILES / InChI

Description

HYDROCHLORIC ACID is formed by dissolving hydrogen chloride gas in water. It is a strong corrosive acid that is commonly used as a laboratory reagent. Also, it constitutes the majority of gastric acid, the human digestive fluid. Skin contact with HYDROCHLORIC ACID can cause redness, pain, and severe skin burns. It may cause severe burns to the eye and permanent eye damage.

Approval Year

1921
1468
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8583
LACTATED RINGER'S

Approved Use

Lactated Ringer’s and 5% Dextrose Injection, USP is indicated as a source of water, electrolytes and calories or as an alkalinizing agent.

Launch Date

1971
PubMed

PubMed

TitleDatePubMed
Catabolism of haemoglobin-haptoglobin complexes in haemolytic uraemia-like syndromes of different etiologies.
1982 Oct
Aging impairs afferent nerve function in rat intestine. Reduction of mesenteric hyperemia induced by intraduodenal capsaicin and acid.
1996 Feb
Substance P may attenuate gastric hyperemia by a mast cell-dependent mechanism in the damaged gastric mucosa.
1999 Nov
Effect of vitamin E on aspirin-induced gastric mucosal injury in rats.
2000 Mar
The protease-activated receptor-2 agonist induces gastric mucus secretion and mucosal cytoprotection.
2001 Jun
Bile-induced adenosine triphosphate depletion and mucosal damage during reflux esophagitis.
2001 May
Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation.
2002 Aug
Protective role of vanilloid receptor type 1 in HCl-induced gastric mucosal lesions in rats.
2004 Apr
Expression of a 72-kDa heat shock protein, and its cytoprotective function, in gastric mucosa in cirrhotic rats.
2004 Aug
The effects of aspirin on gastric mucosal integrity, surface hydrophobicity, and prostaglandin metabolism in cyclooxygenase knockout mice.
2004 Jul
Effects of celecoxib on acid-challenged gastric mucosa of rats: comparison with metamizol and piroxicam.
2004 Jun
Jejunal afferent nerve sensitivity in wild-type and TRPV1 knockout mice.
2004 Nov 1
Pulmonary aspiration: new therapeutic approaches in the experimental model.
2005 Sep
Renal expression of the ammonia transporters, Rhbg and Rhcg, in response to chronic metabolic acidosis.
2006 Feb
Genetic evidence for a protective role of heat shock factor 1 against irritant-induced gastric lesions.
2007 Apr
Effect of prone position without PEEP on oxygenation and complacency in an experimental model.
2007 Jul-Aug
Spontaneous hypersensitivity in mesenteric afferent nerves of mice deficient in the sst2 subtype of somatostatin receptor.
2007 Jun 1
Beneficial effects of suplatast tosilate (IPD-1151T) in a rat cystitis model induced by intravesical hydrochloric acid.
2007 Oct
Bladder afferent sensitivity in wild-type and TRPV1 knockout mice.
2007 Sep 1
Muscarinic receptors involved in airway vascular leakage induced by experimental gastro-oesophageal reflux.
2008 Apr 23
Lung injury and recovery in a murine model of unilateral acid aspiration: functional, biochemical, and morphologic characterization.
2008 Jun
Lactic acid increases aquaporin 4 expression on the cell membrane of cultured rat astrocytes.
2008 May
Permissive hypercapnia, instituted via reduction of pressure amplitude on pulmonary tissue protection during high frequency oscillatory ventilation, is not protective in a rat model of acid-induced lung injury.
2009 Aug
Gastroprotective activity of alkaloid extract and 2-phenylquinoline obtained from the bark of Galipea longiflora Krause (Rutaceae).
2009 Jul 15
Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man.
2009 Oct
Proton acts as a neurotransmitter for nicotine-induced adrenergic and calcitonin gene-related peptide-containing nerve-mediated vasodilation in the rat mesenteric artery.
2009 Sep
Role of the Rhesus glycoprotein, Rh B glycoprotein, in renal ammonia excretion.
2010 Nov
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis.
2010 Oct
Chemicals inducing acute irritant contact dermatitis mobilize intracellular calcium in human keratinocytes.
2013 Feb
Patents

Patents

03931143
18
03931151
3
03931217
11
03931239
40
03932426
35
03932479
113
03932524
68
03932644
2
03933802
2
03933906
2
03934024
2
03936418
3
03937704
32
03940411
10
03940421
2
03940486
2
03943154
10
03946001
3
03947417
2
03947445
3
03947582
13
03948955
2
03950380
3
03950390
2
03950393
3
03950406
119
03950423
2
03951976
2
03951980
4
03953402
2
Name Type Language
Hydrochloric Acid
FCC   HSDB   II   INCI   MART.   MI   VANDF   WHO-DD   WHO-IP  
INCI  
Official Name English
MURIATICUM ACIDUM
HPUS  
Preferred Name English
BAUME HCL
Common Name English
E-507
Code English
HYDROCHLORIC ACID [MART.]
Common Name English
MURIATICUM ACIDUM [HPUS]
Common Name English
ACIDUM HYDROCHLORICUM [WHO-IP LATIN]
Common Name English
HYDROCHLORIC ACID [JAN]
Common Name English
ICON ETCH
Common Name English
HYDROCHLORIC ACID [WHO-IP]
Common Name English
HYDROCHLORIC ACID [VANDF]
Common Name English
INS-507
Code English
INS NO.507
Code English
HYDROCHLORIC ACID [FCC]
Common Name English
ANHYDROUS HYDROCHLORIC ACID
Common Name English
HYDROCHLORIC ACID [IARC]
Common Name English
HYDROGEN CHLORIDE
MI  
Systematic Name English
MURIATIC ACID
Common Name English
HYDROCHLORIC ACID [MI]
Common Name English
HYDROGEN CHLORIDE [MI]
Common Name English
HYDROCHLORIC ACID [II]
Common Name English
HYDROCHLORIC ACID [HSDB]
Common Name English
NSC-77365
Code English
Hydrochloric acid [WHO-DD]
Common Name English
ENPLATE PO 236
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 45901
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
WHO-VATC QB05XA13
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
WHO-VATC QA09AB03
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
DSLD 1445 (Number of products:1)
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
JECFA EVALUATION INS-507
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
WHO-ATC A09AB03
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
WHO-ATC B05XA13
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-507
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
FDA ORPHAN DRUG 98896
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
Code System Code Type Description
EVMPD
SUB50009
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
CONCEPT Industrial Aid
WHO INTERNATIONAL PHARMACOPEIA
HYDROCHLORIC ACID
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY Description: A clear, colourless, fuming liquid; odour, pungent. Miscibility: Miscible with water. Category: Acidifying agent. Storage: Hydrochloric acid should be kept in a tightly closed container. Additional information: The fumes and odour disappear when the acid is diluted with 2 volumes of water. Mass density: .RHO.20 = about 1.18 g/mL. Requirement: Hydrochloric acid contains not less than 35.0% m/mand not more than the equivalent of 38.0% m/mof HCl.
DRUG CENTRAL
4568
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
RXCUI
5486
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY RxNorm
WIKIPEDIA
HYDROCHLORIC ACID
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
NCI_THESAURUS
C76716
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
EVMPD
SUB129759
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
ALTERNATIVE
PUBCHEM
313
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PRIMARY
CAS
7647-01-0
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
CHEBI
17883
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
MERCK INDEX
m6101
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID2020711
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PRIMARY
DAILYMED
QTT17582CB
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
ChEMBL
CHEMBL1231821
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
ECHA (EC/EINECS)
231-595-7
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PRIMARY
MERCK INDEX
m6088
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY Merck Index
MESH
D006851
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
EVMPD
SUB12513MIG
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
FDA UNII
QTT17582CB
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
DRUG BANK
DB13366
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
NSC
77365
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
SMS_ID
100000078724
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
NIH
NCATS
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