U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 31 - 40 of 70 results

Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Conditions:

β-Hexachlorcyclohexane is a byproduct of the production of insecticide lindane (γ-hexachlorocyclohexane). Technical grade hexachlorocyclohexane contains about 5-12% of technical grade hexachlorocyclohecane. Elevated levels of β-Hexachlorcyclohexane in blood was linked with risk of Alzheimer's disease and Parkinson's disease. β-Hexachlorcyclohexane is a xenoestrogen and promotes growth and invasiveness of breast tumor cell lines.
Status:
Other

Class (Stereo):
CHEMICAL (RACEMIC)

Status:
Other

Class (Stereo):
CHEMICAL (ABSOLUTE)


Conditions:

β-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp. β-Zearalenol is the β epimer of α-zearalenol and along with α-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during the first-pass metabolism. β-Zearalenol is about the same or slightly less potent as an estrogen relative to zearalenone. Contamination of grains by Fusarium species, notably maize, gives rise to high levels of zearalenol and is regarded as an important food quality issue for both human and animal health.
Status:
Other

Class (Stereo):
CHEMICAL (ACHIRAL)

Status:
US Previously Marketed
Source:
21 CFR 310.545(a)(20) weight control valine
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Valine is an α-amino acid that is used in the biosynthesis of proteins. It is essential in humans, meaning the body cannot synthesize it and thus it must be obtained from the diet. There is a mixed scientivic evidence that as a dietary supplement valine improves training efficacy, delays central fatigue.
Status:
US Previously Marketed
Source:
Cytellin by Lilly
(1956)
Source URL:
First approved in 1956
Source:
Cytellin by Lilly
Source URL:

Class (Stereo):
CHEMICAL (ABSOLUTE)



Beta-sitosterol is one of the main dietary phytosterols found in plants which have a similar skeleton as cholesterol. In human clinical trials, beta-sitosterol has been shown to have cholesterol-lowering effects and to relieve symptoms of benign prostatic hyperplasia. There has been a large amount of basic research conducted for potential applications of beta-sitosterol in a diverse range of conditions including cervical cancer, breast cancer, cystic fibrosis, and others. Beta-sitosterol is available over the counter as a natural health supplement and is marketed for a wide range of applications including headaches, tuberculosis, allergies, cancers, fibromyalgia, lupus, asthma, hair loss and many others.
Status:
Possibly Marketed Outside US
Source:
Cellapy Haircell Meso Tonic by Gm Holdings Co., Ltd
(2016)
Source URL:
First approved in 2010

Class (Stereo):
CHEMICAL (ACHIRAL)

Zilpaterol is an agonist of β2-adrenergic receptor. Zilpaterol exerts bronchospasmolytic action. Zilmax® (4.8% Zilpaterol hydrochloride) is used to increase rate of bodyweight gain, improve feed efficiency, and increase carcass leanness in cattle fed in confinement for a period of 20-40 consecutive days at the end of the feeding period before slaughter.