BETA-1 ADRENERGIC RECEPTOR

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 11:38:40 UTC 2023` Edited by `admin` on `Sat Dec 16 11:38:40 UTC 2023`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	4A4MK4KIB5
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BETA-1 ADRENERGIC RECEPTOR

Common Name

English

ADRB1

Common Name

English

B1AR

Common Name

English

BETA-1

Common Name

English

beta1

Common Name

English

ADRB1R

Common Name

English

Code System Code Type Description

WIKIPEDIA

BETA-1_ADRENERGIC_RECEPTOR

Created by admin on Sat Dec 16 11:38:42 UTC 2023 , Edited by admin on Sat Dec 16 11:38:42 UTC 2023

PRIMARY

PHAROS

P08588

Created by admin on Sat Dec 16 11:38:42 UTC 2023 , Edited by admin on Sat Dec 16 11:38:42 UTC 2023

PRIMARY

FDA UNII

4A4MK4KIB5

Created by admin on Sat Dec 16 11:38:42 UTC 2023 , Edited by admin on Sat Dec 16 11:38:42 UTC 2023

PRIMARY

UNIPROT

P08588

Created by admin on Sat Dec 16 11:38:42 UTC 2023 , Edited by admin on Sat Dec 16 11:38:42 UTC 2023

PRIMARY

From	To
1_131	1_216
1_209	1_215

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_15

Related Record Type Details


					P1T1143877

MIBENRATIDE

INHIBITOR -> TARGET

Amount:


					R89UMZ82MJ

CGP-12177, (±)-

INHIBITOR -> TARGET

Amount:


					9Y8NXQ24VQ

PROPRANOLOL

INHIBITOR -> TARGET

Amount:


					5ZZ84GCW8B

FORMOTEROL

AGONIST -> TARGET

Amount:


					0K47UL67F2

CARVEDILOL

AGONIST -> TARGET

Amount:


					Y41JS2NL6U

BISOPROLOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					46OL1UC10R

Zenidolol

INHIBITOR -> TARGET

Qualification:

IC50

Amount:


					L628TT009W

ISOPROTERENOL

AGONIST -> TARGET


					030Y90569U

NEBIVOLOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					MDY902UXSR

ESMOLOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					L2JY6Z298S

ERSENTILIDE

INHIBITOR -> TARGET

Amount:


					V5F60UPD8P

DENOPAMINE

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					3S12J47372

DOBUTAMINE

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					U29GY32XJ4

NAVAFENTEROL

AGONIST -> TARGET

Amount:


					0LW22W2PGO

CGP-12177 C-11, (S)-

RADIOLIGAND->TARGET


					7HE0JQL703

XAMOTEROL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					34ZXW6ZV21

BEVANTOLOL

INHIBITOR -> TARGET

Amount:


					588N0603CT

LEVISOPRENALINE

AGONIST -> TARGET

Comments:

Mouse receptor value

Qualification:

Amount:


					597QB6RUS5

CGP-12177 C-11

RADIOLIGAND->TARGET

Comments:

Used for cardiac PET adrenoreceptor imaging studies

Amount:


					L628TT009W

ISOPROTERENOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					N2822NU8E4

L-643717 FREE BASE

LIGAND->TARGET

Amount:


					50VV3VW0TI

ATENOLOL

INHIBITOR -> TARGET

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					I43D0296P8

DEXNEBIVOLOL

INHIBITOR -> TARGET

Amount:


					O0ZR1R6RZ2

BETAXOLOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					62NWQ924LH

Landiolol

INHIBITOR -> TARGET

Amount:


					A6D97U294I

SOTALOL

INHIBITOR -> TARGET


					YKH834O4BH

EPINEPHRINE

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					67P356D8GH

ACEBUTOLOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					GEB06NHM23

METOPROLOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					G6317AOI7K

LEVOBUNOLOL

ANTAGONIST->TARGET

Comments:

Levobunolol (LB) is the levo-rotatory isomer of bunolol, a potent, nonselective antagonist of beta-adrenergic receptors.


					50VV3VW0TI

ATENOLOL

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					SIO2UEZ19H

CGP-20712

INHIBITOR -> TARGET

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					Z7YP8B158Q

CGP-12177, (S)-

INHIBITOR -> TARGET

Interaction Type:

BINDING

Qualification:

Amount:


					D6P84R4E5Y

Iodocyanopindolol I-125

RADIOLIGAND->TARGET

Comments:

Chinese hamster ovary (CHO) cells stably expressing the three β-adrenergic receptor subtypes at comparable levels.

Qualification:

Amount:


					R5H8897N95

LABETALOL

INHIBITOR -> TARGET

Amount:


					5NVQ63ZG89

(-)-CGP-12177 H-3

RADIOLIGAND->TARGET

Qualification:

Amount:


					DPF757BOSR

ESATENOLOL

INHIBITOR -> TARGET

Amount:


					WP4LUA5RAK

Iodocyanopindolol

INHIBITOR -> TARGET

Comments:

Chinese hamster ovary (CHO) cells stably expressing the three β-adrenergic receptor subtypes at comparable levels.

Qualification:

Amount:


					B6CJY5K2ST

ADIMOLOL

INHIBITOR -> TARGET

Amount:


					J7A92W69L7

DROXIDOPA

AGONIST -> TARGET

Amount:


					X4W3ENH1CV

NOREPINEPHRINE

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					0K47UL67F2

CARVEDILOL

INHIBITOR -> TARGET

Amount:


					3O2K1S3WQV

VORTIOXETINE

AGONIST -> TARGET

Interaction Type:

SHORT-ACTING

Amount:


					8MCV2NLH7Z

CGP-12388 C-11

RADIOLIGAND->TARGET

Comments:

Used for cardiac PET adrenoreceptor imaging studies

Amount:


					5JKY92S7BR

TIMOLOL ANHYDROUS

AGONIST -> TARGET

Comments:

NON-SELECTIVE

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL