U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

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Showing 311 - 320 of 345 results

Status:
US Previously Marketed
First approved in 1994
Source:
IOBENGUANE SULFATE I 131 by PHARMALUCENCE
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Iobenguane I-131 is a radioactive therapeutic agent. The drug contains radioactive isotope I-131, which decays by electron emission with a half-life of about 8 days. By the chemical structure, iobenguane is similar to the neurotransmitter norepinephrine and is subject to the same uptake and regulation pathways. After intravenous administration, iobenguane I-131 accumulates within pheochromocytoma and paraganglioma cells, and radiation from the radioactive decay causes cell death and tumor necrosis. Iobenguane I-131 was approved by the FDA for the treatment of adult and pediatric patients with iobenguane scan positive, unresectable, locally advanced or metastatic pheochromocytoma or paraganglioma who require systemic anticancer therapy. Iobenguane I-131 is investigated in clinical trials as a treatment of neuroblastoma, ganglioneuroblastoma and other tumors of neuroendocrinal origin.
Status:
US Previously Marketed
Source:
Sucaryl Calcium by Abbott
(1953)
Source URL:
First approved in 1953
Source:
Sucaryl Calcium by Abbott
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

CALCIUM CYCLAMATE, a salt of cyclamic acid, is an artificial sweetener. Cyclamates and its salts (such as calcium cyclamate, sodium cyclamate, magnesium cyclamate, and potassium cyclamate) are currently prohibited from use in the United States.
Phenylpropanolamine belongs to the sympathomimetic amine class of drugs and is structurally related to ephedrine. The effects of phenylpropanolamine are largely the result of alpha-adrenergic agonist activity resulting from both direct stimulation of adrenergic receptors and release of neuronal norepinephrine. Phenylpropanolamine is mainly used as a nasal decongestant. Phenylpropanolamine is also used as anorexiant in obesity and to treat urinary incontinence in veteranary. Phenylpropanolamine containing products has been withdrawn by FDA due to the association of phenylpropanolamine use with increased risk of hemorrhagic stroke.
Status:
US Previously Marketed
Source:
Corrosive Mercuric Chloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Corrosive Mercuric Chloride U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Potassium Triiodomercurate(II) is a periodometallate salt. It contains a triiodomercurate(1-). It is an antiseptic (topical) and disinfectant. It is also an antiseborrheic agent.
Status:
US Previously Marketed
Source:
Lead Iodide N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Lead Iodide N.F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


There is no information related to biological or pharmacological application of lead(II) bromide (a combustion product of the gasoline additives lead (IV) tetraethyl and 1,2-dibromoethane). It is only known, that this substance possesses mutagenicity.
Status:
US Previously Marketed
Source:
Lead Iodide N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Lead Iodide N.F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


There is no information related to biological or pharmacological application of lead(II) bromide (a combustion product of the gasoline additives lead (IV) tetraethyl and 1,2-dibromoethane). It is only known, that this substance possesses mutagenicity.
Status:
US Previously Marketed
Source:
Lead Iodide N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Lead Iodide N.F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


There is no information related to biological or pharmacological application of lead(II) bromide (a combustion product of the gasoline additives lead (IV) tetraethyl and 1,2-dibromoethane). It is only known, that this substance possesses mutagenicity.
Status:
US Previously Marketed
Source:
Lead Iodide N.F.
(1921)
Source URL:
First marketed in 1921
Source:
Lead Iodide N.F.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


There is no information related to biological or pharmacological application of lead(II) bromide (a combustion product of the gasoline additives lead (IV) tetraethyl and 1,2-dibromoethane). It is only known, that this substance possesses mutagenicity.
Status:
US Previously Marketed
Source:
Corrosive Mercuric Chloride U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Corrosive Mercuric Chloride U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)

Potassium Triiodomercurate(II) is a periodometallate salt. It contains a triiodomercurate(1-). It is an antiseptic (topical) and disinfectant. It is also an antiseborrheic agent.
Status:
US Previously Marketed
Source:
Solution of Lead Subacetate U.S.P.
(1921)
Source URL:
First marketed in 1921
Source:
Solution of Lead Subacetate U.S.P.
Source URL:

Class (Stereo):
CHEMICAL (ACHIRAL)


Lead(II) acetate is a white crystalline chemical compound with a sweetish taste. Lead(II) acetate is used as a mordant in textile printing and dyeing, as a drier in paints and varnishes, and in preparing other lead compounds. It was historically used as a sweetener and for cosmetics.

Showing 311 - 320 of 345 results