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Details

Stereochemistry ACHIRAL
Molecular Formula 2C6H12NO3S.Ca.2H2O
Molecular Weight 432.567
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CALCIUM CYCLAMATE

SMILES

O.O.[Ca++].[O-]S(=O)(=O)NC1CCCCC1.[O-]S(=O)(=O)NC2CCCCC2

InChI

InChIKey=RBTQJTVPZBDPIF-UHFFFAOYSA-L
InChI=1S/2C6H13NO3S.Ca.2H2O/c2*8-11(9,10)7-6-4-2-1-3-5-6;;;/h2*6-7H,1-5H2,(H,8,9,10);;2*1H2/q;;+2;;/p-2

HIDE SMILES / InChI
Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C6H13NO3S
Molecular Weight 179.237
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

CALCIUM CYCLAMATE, a salt of cyclamic acid, is an artificial sweetener. Cyclamates and its salts (such as calcium cyclamate, sodium cyclamate, magnesium cyclamate, and potassium cyclamate) are currently prohibited from use in the United States.

Approval Year

1953
193
Cmax

Cmax

ValueDoseCo-administeredAnalytePopulation
400 ng/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/1379387/
2.2 g 3 times / day steady-state, oral
dose: 2.2 g
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
CYCLOHEXYLAMINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
AUC

AUC

ValueDoseCo-administeredAnalytePopulation
1912 ng × h/mL
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/1379387/
2.2 g 3 times / day steady-state, oral
dose: 2.2 g
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
CYCLOHEXYLAMINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
T1/2

T1/2

ValueDoseCo-administeredAnalytePopulation
4 h
EXPERIMENT
https://pubmed.ncbi.nlm.nih.gov/1379387/
2.2 g 3 times / day steady-state, oral
dose: 2.2 g
route of administration: Oral
experiment type: STEADY-STATE
co-administered:
CYCLOHEXYLAMINE plasma
Homo sapiens
population: UNHEALTHY
age: ADULT
sex: FEMALE / MALE
food status: UNKNOWN
Sourcing

Sourcing

Vendor/AggregatorIDURL
3B Scientific (Wuhan) Corp
3B3-024225
http://www.3bsc.com/index/pro_info.php?id=45302
AAA Chemistry
AR-1I1566
ABI Chem
AC1L1RMG
AHH Chemical co.,ltd
MT-04317
http://www.ahhchemical.com/product/MT-04317.html
Ambinter
Amb22729880
http://www.ambinter.com/reference/22729880
AN PharmaTech
AN-23152
BOC Sciences
139-06-0
https://www.bocsci.com/calcium-cyclamate-cas-139-06-0-item-9833.html
ChemMol
49415939
http://www.chemmol.com/chemmol/49415939.html
ChemTik
CTK4E3343
Debye Scientific
DB-042461
http://www.debyesci.com/cas_139-06-0.html
Finetech
FT-0631808
http://www.finetechnology-ind.com/prod/detail/pub/139-06-0.html
iChemical
EBD47212
http://www.ichemical.com/chemicals/cas-139-06-0
MP Biomedicals
212617
MuseChem
M068972
https://www.musechem.com/product/M068972.html
NovoSeek
8752
PubChem
8752
https://pubchem.ncbi.nlm.nih.gov/compound/8752
Patents

Patents

20080076185
2
20090281195
12
20110251426
10
20110257430
6
7452555
3
7744815
2
8350085
2
WO2007038524A2
7
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:34:37 GMT 2025
Edited
by admin
on Mon Mar 31 17:34:37 GMT 2025
Record UNII
OK71859Z12
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CALCIUM CYCLAMATE
II   MART.   WHO-DD  
INCI  
Official Name English
CALCIUM CYCLAMATE DIHYDRATE
MART.   MI  
Preferred Name English
CYCLAMATE CALCIUM DIHYDRATE
Common Name English
CALCIUM CYCLAMATE [II]
Common Name English
Calcium cyclamate [WHO-DD]
Common Name English
CALCIUM CYCLOHEXANESULFAMATE DIHYDRATE
Common Name English
INS-952(II)
Code English
E-952(II)
Code English
CALCIUM CYCLAMATE DIHYDRATE [MI]
Common Name English
CALCIUM CYCLAMATE [USP-RS]
Common Name English
CALCIUM CYCLOHEXYLSULFAMATE DIHYDRATE
Systematic Name English
CALCIUM N-CYCLOHEXYLSULPHAMATE DIHYDRATE
Systematic Name English
CYCLOHEXANESULFAMIC ACID, CALCIUM SALT (2:1), DIHYDRATE
Common Name English
INS NO.952(II)
Code English
CALCIUM CYCLAMATE [MART.]
Common Name English
CALCIUM CYCLAMATE DIHYDRATE [MART.]
Common Name English
SULFAMIC ACID, CYCLOHEXYL-, CALCIUM SALT (2:1), DIHYDRATE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C283
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
JECFA EVALUATION INS-952(II)
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
CFR 21 CFR 189.135
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
Code System Code Type Description
FDA UNII
OK71859Z12
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
CAS
5897-16-5
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
CODEX ALIMENTARIUS (GSFA)
INS-952(II)
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY CYCLAMATES
RXCUI
155015
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY RxNorm
PUBCHEM
22186
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
RS_ITEM_NUM
1086447
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
MERCK INDEX
m2937
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID70207706
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
WIKIPEDIA
Calcium cyclamate
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
EVMPD
SUB13172MIG
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
NCI_THESAURUS
C77136
Created by admin on Mon Mar 31 17:34:37 GMT 2025 , Edited by admin on Mon Mar 31 17:34:37 GMT 2025
PRIMARY
Related Record Type Details
Structure of CYCLAMIC ACID
PARENT -> SALT/SOLVATE
NIH
NCATS
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