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Restrict the search for
ganciclovir
to a specific field?
Status:
US Previously Marketed
Source:
STOXIL by GLAXOSMITHKLINE
(1967)
Source URL:
First approved in 1963
Source:
DENDRID by ALCON
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Conditions:
Idoxuridine is an antiviral agent use in keratitis caused by herpes simplex virus. As a prescription drug it comes as a 0.1% ophthalmic solution/drops (Herplex and Dendrid). The first studies of the compound for treatment of human herpes simplex started in early 1960s. Being a structural analog of thymidine idoxuridine inhibits viral DNA replication by substituting thymidine. The effect of idoxuridine results in the inability of the virus to reproduce and/or infect tissues. Idoxuridine also blocks viral thymidine kinase as its substrate analog.
Status:
US Approved Rx
(2018)
Source:
BLA761080
(2018)
Source URL:
First approved in 1991
Source:
BLA103353
Source URL:
Class:
PROTEIN
Status:
Investigational
Source:
NCT03830736: Not Applicable Interventional Completed Postprandial Glucose Regulation
(2019)
Source URL:
Class:
PROTEIN
Status:
Possibly Marketed Outside US
Source:
NCT00464217: Phase 4 Interventional Completed Acute Myeloblastic Leukaemia
(1998)
Source URL:
Class:
PROTEIN
Status:
US Approved Rx
(1990)
First approved in 1990
Class:
STRUCTURALLY DIVERSE
Status:
Investigational
Source:
NCT00693095: Phase 1 Interventional Completed Glioblastoma
(2008)
Source URL:
Class:
STRUCTURALLY DIVERSE
Status:
Other
Class:
STRUCTURALLY DIVERSE
