U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 08:51:54 GMT 2023
Edited
by admin
on Sat Dec 16 08:51:54 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
5840721PJZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OAT-2
Common Name English
OAT2
Common Name English
ORGANIC ANION TRANSPORTER 2
Common Name English
MGC45202
Common Name English
MGC24091
Common Name English
SLC22A7
Common Name English
NLT
Common Name English
NOVEL LIVER TRANSPORTER
Common Name English
Classification Tree Code System Code
UCSF-FDA TRANSPORTAL SLC22A7
Created by admin on Sat Dec 16 08:51:56 GMT 2023 , Edited by admin on Sat Dec 16 08:51:56 GMT 2023
Code System Code Type Description
FDA UNII
5840721PJZ
Created by admin on Sat Dec 16 08:51:56 GMT 2023 , Edited by admin on Sat Dec 16 08:51:56 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_91
Related Record Type Details
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
Showed high in vivo inhibition potential due to the high unbound plasma concentrations attained at clinically relevant doses.
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IC50
TISSUE EXPRESSION->TRANSPORTER
Considerable role along with organic cation transporter 2 (OCT2), in the tubular secretion and thus renal clearance of creatinine.
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
Showed high in vivo inhibition potential due to the high unbound plasma concentrations attained at clinically relevant doses.
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IC50
TISSUE EXPRESSION->TRANSPORTER
INFLUX
INHIBITOR -> TRANSPORTER
IC50
SUBSTRATE -> TRANSPORTER
NON-INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
IC50
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
INHIBITOR -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
SUBSTRATE -> TRANSPORTER
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL