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Restrict the search for
m nalidixic acid
to a specific field?
Class (Stereo):
CHEMICAL (ABSOLUTE)
Dicirenone is an aldosterone antagonist. It is used as a hypotensive agent. Dicirenone inhibited the effects of aldosterone on urinary K(+):Na(+) ratios and the binding of [(3)H]aldosterone to renal cytoplasmic and nuclear receptors. Dicirenone blocked the action of aldosterone on Na-K ATPase. Cytoplasmic binding of [(3)H]aldosterone and dicirenone was similar in magnitude and involved the same set of sites. It had no effect on adrenal steroidogenesis.
Class (Stereo):
CHEMICAL (ACHIRAL)
Iotranic Acid is triiodobenzoic acid derivative with potential application as new cholangiographic contrast media for liver imaging
Status:
Class (Stereo):
CHEMICAL (ACHIRAL)
Ioxotrizoic acid is acylated 3,5-diaminopolyhalobenzoic acid derivative patented by Sterling Drug Inc. as X-ray contrast agent for liver and spleen.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Feloprentan is an endothelin receptor antagonist.
Class (Stereo):
CHEMICAL (ACHIRAL)
Butilfenin is N-substituted iminodiacetic acid derivative that was studied as tridentate ligand to form a technetium-99m complex.
Class (Stereo):
CHEMICAL (RACEMIC)
Metaterol is a beta-adrenoceptor agonist. It exerts sympathomimetic and broncholytic properties.
Status:
Investigational
Source:
INN:metheptazine [INN]
Source URL:
Class (Stereo):
CHEMICAL (MIXED)
Metheptazine was studied as an analgesic agent.
Status:
Investigational
Source:
NCT01107236: Phase 2 Interventional Completed Healthy
(2010)
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Source:
NCT00081952: Phase 1/Phase 2 Interventional Completed Hot Flashes
(2003)
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Norleucine (L-norleucine) is a 2-aminohexanoic acid is an alpha-amino acid that is caproic acid substituted by an amino group at position 2. It derives from a hexanoic acid. It is used experimentally to study protein structure and function. Norleucine appears to inhibit bacterial growth due to incorporation into proteins in place of methionine, as the analogue inhibits methionine incorporation but does not significantly reduce its synthesis. L-norleucine had antiviral activity in thermophile. In vitro and in vivo assays revealed that L-norleucine significantly suppressed metastasis of gastric and breast cancer cells. L-norleucine interacted with hnRNPA2/B1 protein to inhibit the expressions of Twist1 and Snail, two inhibitors of E-cadherin, and promote the E-cadherin expression, leading to the inhibition of tumor metastasis.
Class (Stereo):
CHEMICAL (ABSOLUTE)
Arfalasin or Hoe 409, an angiotensin II (AII) blocker, inhibits the renin release thus delay recovery of urinary osmolality.
