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Restrict the search for
m nalidixic acid
to a specific field?
Class (Stereo):
CHEMICAL (ACHIRAL)
Nicafenine, a quinoline derivative, is an analgesic.
Class (Stereo):
CHEMICAL (ACHIRAL)
FLUFOSAL is an antithrombotic agent.
Class (Stereo):
CHEMICAL (RACEMIC)
Doxaprost is an orally active bronchodilator. Doxaprost was 73 and 32 times more potent that (+/-) 11-deoxy PGE1 by the aerosol and i.v. routes, respectively. Doxaprost also demonstrated a longer duration of effect. Doxaprost is indicated for the treatment of symptoms of benign prostatic hyperplasia and hypertension. Common side effects are: dizziness, weakness and rarely fainting, especially at the beginning of the medication use. Doxaprost potentiates the action of lowering the blood pressure of other alpha-blockers and anti-hypertensives.
Class (Stereo):
CHEMICAL (ACHIRAL)
Drazidox is the antiseptic agent.
Status:
Investigational
Source:
NCT00065312: Phase 2 Interventional Completed Diabetes Mellitus, Non-Insulin-Dependent
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Targets:
Naveglitazar is an oral dual peroxisome proliferator-activated receptor (PPAR) agonist, which was under development with Ligand Pharmaceuticals for the treatment of type 2 diabetes mellitus. Naveglitazar is a nonthiozolidinedione peroxisome proliferator-activated receptor (PPAR) α-γ dual, γ-dominant agonist that has shown glucose-lowering potential in animal models and in the clinic. Naveglitazar had been in phase II clinical trials for the once-daily oral treatment of type 2 diabetes, however, the development was discontinued.
Class (Stereo):
CHEMICAL (ACHIRAL)
Tibenelast is an orally active phosphodiesterase inhibitor that was undergoing phase II clinical trials in the USA as a bronchodilator. In preclinical studies Tibenelast is moderately active against the lung and stomach enzyme while being a very weak inhibitor of the heart enzyme and it does not inhibit enzymes involved in arachidonic acid metabolism. Tibenelast shows potent anti-anaphylactic activity in guinea pigs without cardiovascular effects at the bronchodilatory doses.
Status:
Investigational
Class (Stereo):
CHEMICAL (ACHIRAL)
Tifurac is a benzofuranacetic acid derivative patented by Syntex, Inc. as an analgesic, anti-inflammatory, and antipyretic agent. In preclinical models, Tifurac can exert anti-inflammatory and analgesic activity in rat paw edema assay and mouse writhing assay.
Status:
Investigational
Source:
INN:clorindanic acid [INN]
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Clorindanic acid is a choleretic indanol derivative. Sterling Drug Inc. patented the compound in the 1960s. The compound is claimed to cause an increase in the rate of bile flow when administered to dogs. In rats, clorindanic acid was shown to have mild analgesic activity and hyperthermic effect.
Status:
Investigational
Source:
Tokai J Exp Clin Med. May 1990;15(2-3):123-7.: Not Applicable Human clinical trial Completed Liver Cirrhosis, Alcoholic/physiopathology
Source URL:
Class (Stereo):
CHEMICAL (ACHIRAL)
Status:
Investigational
Source:
Acta Endocrinol (Copenh). 1966;53:Suppl 111:3-26.: Not Applicable Human clinical trial Completed Menstruation Disturbances
Source URL:
Class (Stereo):
CHEMICAL (ABSOLUTE)
Conditions:
Pregnanediol is a chief steroid metabolite of progesterone that is biologically inactive and occurs as pregnanediol glucuronate in the urine. Pregnanediol has two hydroxyl groups, at 3-alpha and 20-alpha. A test can be done to measure the amount of pregnanediol in urine. The urine test offers an indirect way to measure progesterone levels in the body. It is a standard in the colorimetric determination of urinary pregnanediol in clinical laboratories.
