NICAFENINE

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H19ClN4O3
Molecular Weight	446.886
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NICAFENINE

Structure Search

SMILES

ClC1=CC2=NC=CC(NC3=C(C=CC=C3)C(=O)OCCNC(=O)C4=CN=CC=C4)=C2C=C1

InChI

InChIKey=XHMFPDMOPBXSDM-UHFFFAOYSA-N

InChI=1S/C24H19ClN4O3/c25-17-7-8-18-21(9-11-27-22(18)14-17)29-20-6-2-1-5-19(20)24(31)32-13-12-28-23(30)16-4-3-10-26-15-16/h1-11,14-15H,12-13H2,(H,27,29)(H,28,30)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/44470 | https://apps.who.int/iris/bitstream/handle/10665/275695/WHO-EMP-RHT-TSN-2018.1-eng.pdf?sequence=1&isAllowed=y

Nicafenine, a quinoline derivative, is an analgesic.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Nicafenine, a new analgesic. I. Synthesis and physicochemical properties.	1979	44470

Patents

Patents

Name

Type

Language

NICAFENINE

Official Name

English

N-(7-CHLORO-4-QUINOLYL)ANTHRANILIC ACID ESTER WITH N-(2-HYDROXYETHYL)NICOTINAMIDE

Preferred Name

English

nicafenine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241

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Code System Code Type Description

FDA UNII

F1DZD948G6

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SMS_ID

100000084184

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PUBCHEM

68831

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EVMPD

SUB09220MIG

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MESH

C023803

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INN

4534

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ChEMBL

CHEMBL2107151

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CAS

64039-88-9

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NCI_THESAURUS

C75069

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EPA CompTox

DTXSID00214084

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ACTIVE MOIETY


					F1DZD948G6