ETOFENPROX

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H28O3
Molecular Weight	376.488
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC=CC(OC3=CC=CC=C3)=C2

InChI

InChIKey=YREQHYQNNWYQCJ-UHFFFAOYSA-N

InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C25H28O3
Molecular Weight	376.488
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.mitsuichem.com/en/service/packaging/agrochemicals/trebon/index.htm | https://www.centrallifesciences.com/active-ingredients/etofenprox

Etofenprox is a synthetic pyrethroid insecticide compound used in agricultural production. Etofenprox acts on the nervous system of insects by disrupting their neuron sodium channels. Etofenprox is a contact-kill adulticide used to control a wide variety of insects including weevils, beetles, aphids, moths, whiteflies, thrips, borers, fleas and mosquitoes. Etofenprox is well tolerated by mammals, including cats, and is environmentally friendly.

Approval Year

PubMed

Title	Date	PubMed
Liver tumor promoting effect of etofenprox in rats and its possible mechanism of action.	2012	22467020
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.	2011-02-27	21115097
Knockdown resistance in Anopheles vagus, An. sinensis, An. paraliae and An. peditaeniatus populations of the Mekong region.	2010-07-21	20646327
Risk assessment of insecticides used in rice on miridbug, Cyrtorhinus lividipennis Reuter, the important predator of brown planthopper, Nilaparvata lugens (Stal.).	2010-07	20537680
Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays.	2010-07	20410157
Toxicity of the insecticide etofenprox to three life stages of the grass shrimp, Palaemonetes pugio.	2010-05	20300745
Effects of several pyrethroids on hepatic cytochrome P450 activities in rats.	2010-04	20009351
Effectiveness of five insecticides for the control of adults and young stages of Cacopsylla melanoneura (Förster) (Hemiptera: Psyllidae) in a semi-field trial.	2010-03	19937976
Contamination of rice by etofenprox, diethyl phthalate and alkylphenols: effects on first delivery and sperm count in mice.	2010-02	20118624
Acute toxicity to zebrafish of two organophosphates and four pyrethroids and their binary mixtures.	2010-01	19728319
Partitioning of etofenprox under simulated California rice-growing conditions.	2010-01	19685446
Comparative acute toxicity of neonicotinoid and pyrethroid insecticides to non-target crayfish (Procambarus clarkii) associated with rice-crayfish crop rotations.	2009-11	19623546
Impact of insecticide-treated nets on wild pyrethroid resistant Anopheles epiroticus population from southern Vietnam tested in experimental huts.	2009-10-29	19874581
Esterase-mediated resistance to pyrethroids in field populations of Helicoverpa armigera (Lepidoptera: Noctuidae) from Central Africa.	2009-10	19548293
Development of certified reference material for quantification of two pesticides in brown rice.	2009-09-23	19702268
Induction profile of HSP70-cognate genes by environmental pollutants in Chironomidae.	2009-09	21784019
Exposure to pesticides residues from consumption of Italian blood oranges.	2009-07	19680977
QSPR studies on aqueous solubilities of drug-like compounds.	2009-06-03	19582218
Daily variation of pesticides in surface water of a small river flowing through paddy field area.	2009-06	19290454
Impact of etofenprox (Vectron 20 WP) indoor residual spray on malaria transmission.	2009-05	19675390
Absence of knockdown resistance suggests metabolic resistance in the main malaria vectors of the Mekong region.	2009-04-28	19400943
Determination of 142 pesticides in fruit- and vegetable-based infant foods by liquid chromatography/electrospray ionization-tandem mass spectrometry and estimation of measurement uncertainty.	2009-04-23	19382587
Nationwide investigation of the pyrethroid susceptibility of mosquito larvae collected from used tires in Vietnam.	2009	19274072
Fragmentation of a non-ester pyrethroid insecticide by atmospheric pressure chemical ionization.	2009	19174593
Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka.	2008-08-28	18755020
The insecticide resistance status of malaria vectors in the Mekong region.	2008-06-05	18534006
Effect of washing on the bioefficacy of insecticide-treated nets (ITNs) and long-lasting insecticidal nets (LLINs) against main malaria vector Anopheles stephensi by three bioassay methods.	2008-06	18592843
Evaluation of pressurized liquid extraction for the analysis of four pesticides in unpolished rice.	2008-06	18576219
Acute toxicity of organophosphorus and pyrethroid insecticides to Bombyx mori.	2008-04	18459399
Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda.	2008-03-20	18355408
Susceptibility of Culex pipiens complex to some insecticides in Qatar.	2007-12	18383791
Insecticide resistance in potential vector mosquitoes for West Nile virus in Japan.	2007-09	17915515
Safe apples for baby-food production: survey of pesticide treatment regimes leaving minimum residues.	2007-06	17487602
Determination of pesticides in apples by liquid chromatography with electrospray ionization tandem mass spectrometry and estimation of measurement uncertainty.	2007-05-04	17474525
[Evaluation of the residual effect of pyrethroids on Anopheles in the Brazilian Amazon].	2007-04	17384805
Determination of Etofenprox in environmental samples by HPLC after anionic surfactant micelle-mediated extraction (coacervation extraction).	2006-03	16491345
Simultaneous analysis of termiticides in indoor air by using gas chromatography mass spectrometry.	2005-06-01	15986770
Maps of the Sri Lanka malaria situation preceding the tsunami and key aspects to be considered in the emergency phase and beyond.	2005-01-27	15676073
Dosage-dependent effects of permethrin-treated nets on the behaviour of Anopheles gambiae and the selection of pyrethroid resistance.	2004-07-08	15242513
Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables.	2004-05-21	15146917
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.	2004-04	15064155
Insecticide susceptibility tests of Anopheles minimus s.l., Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus in northern Thailand.	2003-03	12971519
Factors involved in the re-emergence of malaria in borderline of Iran, Armenia, Azerbaijan and Turkey.	2003	19238663
Committee on Pesticides and Disinfectant Formulations. Pesticide formulations: CIPAC studies. Collaborative International Pesticide Analytical Council.	2002-03-07	11878608
Activation of a stress-induced gene by insecticides in the midge, Chironomus yoshimatsui.	2002	11857772
Effects of various insecticides on the development of the egg parasitoid Trichogramma dendrolimi (Hymenoptera: Trichogrammatidae).	2001-12	11777034
Effects of organosilicon pyrethroid-like insecticides on nerve preparations of American cockroaches and crayfish.	2001-06	11407026
A monoclonal antibody-based ELISA for the analysis of the insecticide flucythrinate in environmental and crop samples.	2001-03	11455657
An evidence-based vector control strategy for military deployments: the British Army experience.	2001	11584666
Chemistry and specifications of pesticides.	2001	11370550

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:25:23 GMT 2025` Edited by `admin` on `Mon Mar 31 18:25:23 GMT 2025`
Record UNII	0LD7P9153C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ETOFENPROX [MI]

Preferred Name

English

ETOFENPROX

Official Name

English

ETOFENPROX [JAN]

Common Name

English

etofenprox [INN]

Common Name

English

1-((2-(4-ETHOXYPHENYL)-2-METHYLPROPOXY)METHYL)-3-PHENOXYBENZENE

Systematic Name

English

ETOFENPROX [MART.]

Common Name

English

.ALPHA.-((P-ETHOXY-B,B-DIMETHYLPHENETHYL)OXY)-M-PHENOXYTOLUENE

Common Name

English

2-(4-ETHOXYPHENYL)-2-METHYLPROPYL 3-PHENOXYBENZYL ETHER

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

128965